Polycystic ovary syndrome (PCOS) affects about 12% of women of reproductive age. In 2018, the first evidence‐based guideline on assessment and management of PCOS was …
Metformin is a synthetic biguanide used as an antidiabetic drug in type 2 diabetes mellitus, achieved by studying the bioactive metabolites of Galega officinalis L. It is also used off-label …
JR Petrie - Diabetes, Obesity and Metabolism, 2024 - Wiley Online Library
Metformin is best known as a foundational therapy for type 2 diabetes but is also used in other contexts in clinical medicine with a number of emerging and potential indications …
SF de Medeiros, JMS Junior, MAS de Medeiros… - Archives of Gynecology …, 2024 - Springer
Background Polycystic ovary syndrome (PCOS) is a heterogenous endocrine condition and combined oral contraceptives (COCs) have been demonstrated to be the first-line treatment …
J Melin, M Forslund, S Alesi, T Piltonen… - The Journal of …, 2024 - academic.oup.com
De Zegher and Ibanez suggest that metformin should be first-line treatment with the addition of combined oral contraceptive pills (COCPs) if needed for adolescents with polycystic ovary …
Objective To study the combined and isolated effects of melatonin and metformin in the ovarian tissue of rats with PCOS. Design Experimental study using a rat model of PCOS …
M Nizamani, C Nagdev, N Ahmed, A Raza - European Journal of …, 2024 - Elsevier
Isntroduction. Polycystic ovary syndrome (PCOS) is a multifaceted endocrine-gynecological condition affecting a substantial number of women during their reproductive years …
In einer doppelblinden, randomisierten, placebokontrollierten Phase-2-Studie führte der GIP- (glukoseabhängiges insulinotropes Peptid), GLP-1-(glukagonähnliches [„glucagon-like “] …
SF de Medeiros, JMS Junior, MAS de Medeiros… - 2024 - scholar.archive.org
Background. Combined oral contraceptives (COCs) are of rst line treatment of women with polycystic ovary syndrome (PCOS) who do not intend to become pregnant. PCOS is a …