OBJECTIVE: Apathy is highly prevalent among neuropsychiatric populations and is
associated with greater morbidity and worse functional outcomes. Despite this, it remains …

Apathy, or a lack of motivation, has been increasingly recognized as a distinct psychiatric
syndrome. Apathy is primarily a dysfunction of the frontal-subcortical circuit and is …

Background Depression is common, disabling, costly and under‐treated. There are
problems in the current first‐line drug treatment, antidepressants, for moderate or severe …

Background: Alzheimer's disease (AD) is characterized by a number of serious and
debilitating behavioral and psychological symptoms of dementia (BPSD). The most common …

Apathy is a common behavioral symptom of Alzheimer's disease (AD), being present in up to
70% of patients. Apathy in AD and non-AD populations has been associated with …

Cross-sectional studies demonstrate depression is associated with disability in elders.
These studies also report that disability in depressed elders is associated with greater …

Background: Depressive symptoms, fatigue, and apathy are common symptoms among
medically ill older adults and patients with advanced disease, and have been associated …

Objective: The purpose of the present study was to examine the independent influence of
symptoms of depression and apathy, two of the most common neuropsychiatric symptoms in …

Background: There is growing recognition that apathy is not only a symptom of depression
but may be an independent syndrome. This is the first study to investigate the relationship of …

Selective serotonin reuptake inhibitors (SSRIs), commonly used to treat depression, are
associated with loss of motivation, anergy, and lack of curiosity often referred collectively as …