The combination of trimethoprim and sulfamethoxazole (TMP-SMX) is the most effective
regimen for therapy of Pneumocystis pneumonia (PCP). As many patients with PCP are …

Autophagy maintains metabolism in response to starvation, but each nutrient is sensed
distinctly. Amino acid deficiency suppresses mechanistic target of rapamycin complex 1 …

Autophagy is closely associated with the regulation of hepatitis B virus (HBV) replication.
HBV X protein (HBx), a multifunctional regulator in HBV-associated biological processes …

Alzheimer's disease (AD) is currently the seventh leading cause of death worldwide. In this
study, we explored the critical role of autophagy in AD pathology using a streptozotocin …

Aims Dexmedetomidine (DEX), a highly selective and potent α2-adrenergic receptor
agonist, has anti-apoptotic, anti-inflammatory, and anti-oxidative stress effects in diabetes …

Autophagy and apoptosis are interlocked in an extensive crosstalk. Our previous study
demonstrated that hypotonic hypoxia-induced marked apoptosis of a spermatocyte-derived …

Proteolytic cleavage of thyroglobulin (Tg) for thyroid hormone (TH) liberation is followed by
TH release from thyroid follicles into the circulation, enabled by TH transporters. The …

The clinical signs always depend on the location of the tumor and include elevated
intracranial pressure (ICP), focal neurologic deficit, and seizures (focal and/or secondarily …