Comorbidities, multimorbidity and COVID-19
The influence of comorbidities on COVID-19 outcomes has been recognized since the
earliest days of the pandemic. But establishing causality and determining underlying …
earliest days of the pandemic. But establishing causality and determining underlying …
Development trends of human organoid‐based COVID‐19 research based on bibliometric analysis
M Li, Y Yuan, T Zou, Z Hou, L Jin, B Wang - Cell Proliferation, 2023 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), a global pandemic caused by the severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has posed a catastrophic threat …
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has posed a catastrophic threat …
Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19
R Mothes, A Pascual-Reguant, R Koehler… - Nature …, 2023 - nature.com
Prolonged lung pathology has been associated with COVID-19, yet the cellular and
molecular mechanisms behind this chronic inflammatory disease are poorly understood. In …
molecular mechanisms behind this chronic inflammatory disease are poorly understood. In …
Macrophage phagocytosis of SARS-CoV-2-infected cells mediates potent plasmacytoid dendritic cell activation
O García-Nicolás, A Godel, G Zimmer… - Cellular & molecular …, 2023 - nature.com
Early and strong interferon type I (IFN-I) responses are usually associated with mild COVID-
19 disease, whereas persistent or unregulated proinflammatory cytokine responses are …
19 disease, whereas persistent or unregulated proinflammatory cytokine responses are …
Suppressive myeloid cells in SARS-CoV-2 and Mycobacterium tuberculosis co-infection
Epidemiologic data show that both current and previous tuberculosis (TB) increase the risk
of in-hospital mortality from coronavirus disease-2019 (COVID-19), and there is a similar …
of in-hospital mortality from coronavirus disease-2019 (COVID-19), and there is a similar …
Modulation of alveolar macrophage and mitochondrial fitness by medicinal plant-derived nanovesicles to mitigate acute lung injury and viral pneumonia
L Ye, Y Gao, SWF Mok, W Liao, Y Wang… - Journal of …, 2024 - Springer
Acute lung injury (ALI) is generally caused by severe respiratory infection and characterized
by overexuberant inflammatory responses and inefficient pathogens-containing, the two …
by overexuberant inflammatory responses and inefficient pathogens-containing, the two …
[HTML][HTML] Overreactive macrophages in SARS-CoV-2 infection: The effects of ACEI
D Felkle, K Zięba, K Kaleta, J Czaja, A Zyzdorf… - International …, 2023 - Elsevier
Among various factors influencing the course of SARS-CoV-2 infection in humans,
macrophage overactivation is considered the main cause of the cytokine storm that leads to …
macrophage overactivation is considered the main cause of the cytokine storm that leads to …
Does autonomous macrophage-driven inflammation promote alveolar damage in COVID-19?
DH Dockrell, CD Russell, B McHugh… - European Respiratory …, 2022 - Eur Respiratory Soc
SARS-CoV-2 has caused devastating effects, with over 550 million infections by July 2022
and approximately 6.4 million deaths [1]. Societal and economic impacts will reverberate for …
and approximately 6.4 million deaths [1]. Societal and economic impacts will reverberate for …
A prospective study of extraesophageal reflux and potential microaspiration in patients hospitalized with COVID-19 in Jordan
H Al-Momani, S Mashal, D Al Balawi, M Almasri… - BMC Pulmonary …, 2023 - Springer
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung infection
has represented a global challenge. Intriguingly, it has been shown that the alveolar lung …
has represented a global challenge. Intriguingly, it has been shown that the alveolar lung …
In vitro and in vivo effects of Pelargonium sidoides DC. root extract EPs® 7630 and selected constituents against SARS-CoV-2 B.1, Delta AY.4/AY.117 and Omicron …
The occurrence of immune-evasive SARS-CoV-2 strains emphasizes the importance to
search for broad-acting antiviral compounds. Our previous in vitro study showed that …
search for broad-acting antiviral compounds. Our previous in vitro study showed that …