The application of biomaterials in biomedicine currently suffers some drawbacks, such as
inflammation and immunological responses due to mismatching and/or limited compatibility …

Given their highly porous nature and excellent water retention, hydrogel‐based biomaterials
can mimic critical properties of the native cellular environment. However, their potential to …

Yes-associated protein (YAP) is a key mechanotransduction protein in diverse physiological
and pathological processes; however, a ubiquitous YAP activity regulatory mechanism in …

Injectable hydrogels have gained popularity for their controlled release, targeted delivery,
and enhanced mechanical properties. They hold promise in cardiac regeneration, joint …

Osteochondral tissue engineering has become a promising strategy for repairing focal
chondral lesions and early osteoarthritis (OA), which account for progressive joint pain and …

Stimuli responsive polymer hydrogels have sparked a considerable interest for biomedical
applications. In this work, we present a novel injectable thermal responsive hydrogel based …

Research on synthetic bioactive bone graft materials has significantly expanded in the past
decade. In this study, the nanocomposite scaffold of semi-interpenetrating networks (semi …

In this era of nanoscience, advances of nanotechnology have led to the creation of new
generations of nanostructures, each characterized by their explorative utilization in various …

Millions of patients worldwide remain inadequately treated for bone defects related to factors
such as disease or trauma. The drawbacks of metallic implant and autograft/allograft use …

Addition of melamine formaldehyde (MF) as a crosslinker containing hydroxymethyl to
partially hydrolyzed poly (acrylamide)(HPAM) generated covalently crosslinked in situ gels …