1H-Detected Biomolecular NMR under Fast Magic-Angle Spinning
T Le Marchand, T Schubeis, M Bonaccorsi… - Chemical …, 2022 - ACS Publications
Since the first pioneering studies on small deuterated peptides dating more than 20 years
ago, 1H detection has evolved into the most efficient approach for investigation of …
ago, 1H detection has evolved into the most efficient approach for investigation of …
How does it really move? Recent progress in the investigation of protein nanosecond dynamics by NMR and simulation
Nuclear magnetic resonance (NMR) spin relaxation experiments currently probe molecular
motions on timescales from picoseconds to nanoseconds. The detailed interpretation of …
motions on timescales from picoseconds to nanoseconds. The detailed interpretation of …
Disulfide-bond-induced structural frustration and dynamic disorder in a peroxiredoxin from MAS NMR
L Troussicot, A Vallet, M Molin… - Journal of the …, 2023 - ACS Publications
Disulfide bond formation is fundamentally important for protein structure and constitutes a
key mechanism by which cells regulate the intracellular oxidation state. Peroxiredoxins …
key mechanism by which cells regulate the intracellular oxidation state. Peroxiredoxins …
The intriguing molecular dynamics of Cer [EOS] in rigid skin barrier lipid layers requires improvement of the model
Omega-O-acyl ceramides such as 32-linoleoyloxydotriacontanoyl sphingosine (Cer [EOS])
are essential components of the lipid skin barrier, which protects our body from excessive …
are essential components of the lipid skin barrier, which protects our body from excessive …
[HTML][HTML] Protein dynamics detected by magic-angle spinning relaxation dispersion NMR
Magic-angle spinning (MAS) nuclear magnetic resonance (NMR) is establishing itself as a
powerful method for the characterization of protein dynamics at the atomic scale. We discuss …
powerful method for the characterization of protein dynamics at the atomic scale. We discuss …
A method to construct the dynamic landscape of a bio-membrane with experiment and simulation
Biomolecular function is based on a complex hierarchy of molecular motions. While
biophysical methods can reveal details of specific motions, a concept for the comprehensive …
biophysical methods can reveal details of specific motions, a concept for the comprehensive …
The Rigid Core and Flexible Surface of Amyloid Fibrils Probed by Magic‐Angle‐Spinning NMR Spectroscopy of Aromatic Residues
Aromatic side chains are important reporters of the plasticity of proteins, and often form
important contacts in protein–protein interactions. We studied aromatic residues in the two …
important contacts in protein–protein interactions. We studied aromatic residues in the two …
Towards a native environment: structure and function of membrane proteins in lipid bilayers by NMR
Solid-state NMR (ssNMR) is a versatile technique that can be used for the characterization
of various materials, ranging from small molecules to biological samples, including …
of various materials, ranging from small molecules to biological samples, including …
Mechanistic Insights into Microsecond Time-Scale Motion of Solid Proteins Using Complementary 15N and 1H Relaxation Dispersion Techniques
NMR relaxation dispersion methods provide a holistic way to observe microsecond time-
scale protein backbone motion both in solution and in the solid state. Different nuclei (1H …
scale protein backbone motion both in solution and in the solid state. Different nuclei (1H …
Recent advances in solid-state relaxation dispersion techniques
P Rovo - Solid State Nuclear Magnetic Resonance, 2020 - Elsevier
This review describes two rotating-frame (R 1 ρ) relaxation dispersion methods, namely the
Bloch-McConnell Relaxation Dispersion and the Near-rotary Resonance Relaxation …
Bloch-McConnell Relaxation Dispersion and the Near-rotary Resonance Relaxation …