Endometrial function in women with polycystic ovary syndrome: a comprehensive review

S Palomba, TT Piltonen… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Polycystic ovary syndrome (PCOS) is the most common cause of
anovulatory infertility. An endometrial component has been suggested to contribute to …

Metformin and insulin resistance: a review of the underlying mechanisms behind changes in GLUT4-mediated glucose transport

R Herman, NA Kravos, M Jensterle, A Janež… - International journal of …, 2022 - mdpi.com
Metformin is the most commonly used treatment to increase insulin sensitivity in insulin-
resistant (IR) conditions such as diabetes, prediabetes, polycystic ovary syndrome, and …

Hyperinsulinemia: an early indicator of metabolic dysfunction

DD Thomas, BE Corkey, NW Istfan… - Journal of the …, 2019 - academic.oup.com
Hyperinsulinemia is strongly associated with type 2 diabetes. Racial and ethnic minority
populations are disproportionately affected by diabetes and obesity-related complications …

Role of the PI3K-Akt signaling pathway in the pathogenesis of polycystic ovary syndrome

T Li, H Mo, W Chen, L Li, Y Xiao… - Reproductive …, 2017 - journals.sagepub.com
This review aimed to focus on the recent progress of the understanding of the role of
phosphatidylinositol 3-kinase (PI3K) in polycystic ovary syndrome (PCOS). In recent years, it …

Systematic review: association of polycystic ovary syndrome with metabolic syndrome and non‐alcoholic fatty liver disease

A Baranova, TP Tran, A Birerdinc… - Alimentary …, 2011 - Wiley Online Library
Aliment Pharmacol Ther 2011; 33: 801–814 Summary Background Polycystic ovary
syndrome (PCOS) is a common disorder for women of child‐bearing age and is associated …

Polycystic ovary syndrome: endometrial markers

TT Piltonen - Best practice & research Clinical obstetrics & …, 2016 - Elsevier
Women with polycystic ovarian syndrome (PCOS) present with several endometrial
abnormalities possibly explaining some of the adverse endometrium-related outcomes in …

Obesity and PCOS: the effect of metabolic derangements on endometrial receptivity at the time of implantation

MMB Schulte, J Tsai, KH Moley - Reproductive Sciences, 2015 - journals.sagepub.com
Successful embryonic implantation is the result of a receptive endometrium, a functional
embryo at the blastocyst stage and a synchronized dialog between maternal and embryonic …

The insulin-sensitizing mechanism of myo-inositol is associated with AMPK activation and GLUT-4 expression in human endometrial cells exposed to a PCOS …

H Cabrera-Cruz, L Oróstica… - American journal …, 2020 - journals.physiology.org
Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disorder characterized by
hyperandrogenism and ovulatory dysfunction but also obesity and hyperinsulinemia. These …

Liuwei Dihuang Pills alleviate the polycystic ovary syndrome with improved insulin sensitivity through PI3K/Akt signaling pathway

Z Qiu, J Dong, C Xue, X Li, K Liu, B Liu, J Cheng… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Polycystic ovary syndrome (PCOS) is a complex
gynecological endocrine disease commonly occurred in women of childbearing age. The …

Research progress on the mechanism between polycystic ovary syndrome and abnormal endometrium

Z Xue, J Li, J Feng, H Han, J Zhao, J Zhang… - Frontiers in …, 2021 - frontiersin.org
As a highly dynamic tissue, the endometrium is periodically shed in response to the
secretion of estrogen and progesterone. After menarche, the endometrium of healthy women …