Neural circuits regulating prosocial behaviors
Positive, prosocial interactions are essential for survival, development, and well-being.
These intricate and complex behaviors are mediated by an amalgamation of neural circuit …
These intricate and complex behaviors are mediated by an amalgamation of neural circuit …
Neurobiology of depression in Parkinson's disease: Insights into epidemiology, molecular mechanisms and treatment strategies
Parkinson's disease (PD) is characterized mainly by motor dysfunctions due to the
progressive loss of dopaminergic neurons. However, PD patients experience a multitude of …
progressive loss of dopaminergic neurons. However, PD patients experience a multitude of …
The role of dopamine and endocannabinoid systems in prefrontal cortex development: Adolescence as a critical period
The prefrontal cortex plays a central role in the control of complex cognitive processes
including action control and decision making. It also shows a specific pattern of delayed …
including action control and decision making. It also shows a specific pattern of delayed …
Potential convergence of olfactory dysfunction in Parkinson's disease and COVID-19: The role of neuroinflammation
H Li, J Qian, Y Wang, J Wang, X Mi, L Qu… - Ageing Research …, 2024 - Elsevier
Parkinson's disease (PD) is a prevalent neurodegenerative disorder that affects 7-10 million
individuals worldwide. A common early symptom of PD is olfactory dysfunction (OD), and …
individuals worldwide. A common early symptom of PD is olfactory dysfunction (OD), and …
Cannabis-based medicine in treatment of patients with Gilles de la Tourette syndrome
Abstract Introduction: Gilles de la Tourette syndrome (GTS) is a childhood onset disorder
characterised by the presence of motor and vocal tics. The guidelines of both the American …
characterised by the presence of motor and vocal tics. The guidelines of both the American …
Addictive drugs modify neurogenesis, synaptogenesis and synaptic plasticity to impair memory formation through neurotransmitter imbalances and signaling …
Drug abuse changes neurophysiological functions at multiple cellular and molecular levels
in the addicted brain. Well-supported scientific evidence suggests that drugs negatively …
in the addicted brain. Well-supported scientific evidence suggests that drugs negatively …
Recent advances in endocannabinoid system targeting for improved specificity: strategic approaches to targeted drug delivery
Opportunities for developing innovative and intelligent drug delivery technologies by
targeting the endocannabinoid system are becoming more apparent. This review provides …
targeting the endocannabinoid system are becoming more apparent. This review provides …
Mobilization of endocannabinoids by midbrain dopamine neurons is required for the encoding of reward prediction
Brain levels of the endocannabinoid 2-arachidonoylglycerol (2-AG) shape motivated
behavior and nucleus accumbens (NAc) dopamine release. However, it is not clear whether …
behavior and nucleus accumbens (NAc) dopamine release. However, it is not clear whether …
Exposure to thimerosal induces behavioral abnormality in the early life stages of zebrafish via altering amino acid homeostasis
X Qiu, Y Zhang, J Gao, Y Cui, K Dong, K Chen… - Journal of Hazardous …, 2024 - Elsevier
Thimerosal (THI) has become a significant source of organic mercury pollutants in aquatic
ecosystems, but there is limited information regarding its adverse effects on fish. In this …
ecosystems, but there is limited information regarding its adverse effects on fish. In this …
[HTML][HTML] Dopamine dysregulation in reward and autism spectrum disorder
K Blum, A Bowirrat, K Sunder, PK Thanos, C Hanna… - Brain Sciences, 2024 - mdpi.com
Autism spectrum disorder (ASD) is primarily characterized by core deficits in social skills,
communication, and cognition and by repetitive stereotyped behaviors. These …
communication, and cognition and by repetitive stereotyped behaviors. These …