Cell-wall recycling of the gram-negative bacteria and the nexus to antibiotic resistance

DA Dik, JF Fisher, S Mobashery - Chemical reviews, 2018 - ACS Publications
The importance of the cell wall to the viability of the bacterium is underscored by the breadth
of antibiotic structures that act by blocking key enzymes that are tasked with cell-wall …

Bacterial battle against acidity

J Schwarz, K Schumacher, S Brameyer… - FEMS Microbiology …, 2022 - academic.oup.com
The Earth is home to environments characterized by low pH, including the gastrointestinal
tract of vertebrates and large areas of acidic soil. Most bacteria are neutralophiles, but can …

Fundamentals and exceptions of the LysR-type transcriptional regulators

W Demeester, B De Paepe, M De Mey - ACS Synthetic Biology, 2024 - ACS Publications
LysR-type transcriptional regulators (LTTRs) are emerging as a promising group of
macromolecules for the field of biosensors. As the largest family of bacterial transcription …

Coordinating carbon and nitrogen metabolic signaling through the cyanobacterial global repressor NdhR

YL Jiang, XP Wang, H Sun, SJ Han… - Proceedings of the …, 2018 - National Acad Sciences
The coordination of carbon and nitrogen metabolism is essential for bacteria to adapt to
nutritional variations in the environment, but the underlying mechanism remains poorly …

Versatility and complexity: common and uncommon facets of LysR-type transcriptional regulators

AC Baugh, C Momany, EL Neidle - Annual Review of …, 2023 - annualreviews.org
LysR-type transcriptional regulators (LTTRs) form one of the largest families of bacterial
regulators. They are widely distributed and contribute to all aspects of metabolism and …

The β-lactamase gene regulator AmpR is a tetramer that recognizes and binds the D-Ala-D-Ala motif of its repressor UDP-N-acetylmuramic acid (MurNAc) …

G Vadlamani, MD Thomas, TR Patel, LJ Donald… - Journal of biological …, 2015 - ASBMB
Inducible expression of chromosomal AmpC β-lactamase is a major cause of β-lactam
antibiotic resistance in the Gram-negative bacteria Pseudomonas aeruginosa and …

LysR-type transcriptional regulators: state of the art

S Mayo-Pérez, Y Gama-Martínez, S Dávila… - Critical Reviews in …, 2024 - Taylor & Francis
The LysR-type transcriptional regulators (LTTRs) are DNA-binding proteins present in
bacteria, archaea, and in algae. Knowledge about their distribution, abundance, evolution …

Resveratrol–a potential inhibitor of biofilm formation in Vibrio cholerae

N Augustine, AK Goel, KC Sivakumar, RA Kumar… - Phytomedicine, 2014 - Elsevier
Resveratrol, a phytochemical commonly found in the skin of grapes and berries, was tested
for its biofilm inhibitory activity against Vibrio cholerae. Biofilm inhibition was assessed using …

Crystal structure of the full‐length LysR‐type transcription regulator CbnR in complex with promoter DNA

EA Giannopoulou, M Senda, MP Koentjoro… - The FEBS …, 2021 - Wiley Online Library
LysR‐type transcription regulators (LTTRs) comprise one of the largest families of
transcriptional regulators in bacteria. They are typically homo‐tetrameric proteins and …

Crystal structures of YeiE from Cronobacter sakazakii and the role of sulfite tolerance in gram-negative bacteria

S Hong, J Kim, E Cho, S Na, YJ Yoo… - Proceedings of the …, 2022 - National Acad Sciences
Cronobacter sakazakii is an emerging gram-negative pathogenic bacterium that causes
meningitis, bacteremia, and necrotizing enterocolitis in infants and has a high mortality rate …