Visual Impairment in Pre-Clinical Models of Mild Traumatic Brain Injury

G Orbach, EJ Melendes, K Warren, J Qiu… - Journal of …, 2024 - liebertpub.com
Impairment in visual function is common after traumatic brain injury (TBI) in the clinical
setting, a phenomenon that translates to pre-clinical animal models as well. In Morris et …

Traumatic brain injury-related optic nerve damage

J Qiu, M Boucher, G Conley, Y Li… - … of Neuropathology & …, 2022 - academic.oup.com
Vision disorders are associated with traumatic brain injury (TBI) in 20%–40% of clinical
cases and involve a diverse set of potential symptoms that can present acutely or …

Cell death, inflammation and oxidative stress in neurodegenerative diseases: mechanisms and cytoprotective molecules

A Vejux - International Journal of Molecular Sciences, 2021 - mdpi.com
Neurodegenerative diseases are the most common chronic neurological pathologies
associated with age, with a major impact on the patient's quality of life. These pathologies …

Human amnionic progenitor cell secretome mitigates the consequence of traumatic optic neuropathy in a mouse model

R McCartan, A Gratkowski, M Browning… - … Therapy Methods & …, 2023 - cell.com
Traumatic optic neuropathy (TON) is a condition in which acute injury to the optic nerve from
direct or indirect trauma results in vision loss. The most common cause of TON is indirect …

Effects of Mild Closed-Head Injury and Subanesthetic Ketamine Infusion on Microglia, Axonal Injury, and Synaptic Density in Sprague–Dawley Rats

M Boese, RY Berman, J Qiu, HF Spencer… - International Journal of …, 2024 - mdpi.com
Mild traumatic brain injury (mTBI) affects millions of people in the US Approximately 20–30%
of those individuals develop adverse symptoms lasting at least 3 months. In a rat mTBI study …

A Siamese Convolutional Neural Network for Identifying Mild Traumatic Brain Injury and Predicting Recovery

F Koochaki, L Najafizadeh - IEEE Transactions on Neural …, 2024 - ieeexplore.ieee.org
Timely diagnosis of mild traumatic brain injury (mTBI) remains challenging due to the rapid
recovery of acute symptoms and the absence of evidence of injury in static neuroimaging …

[HTML][HTML] Repetitive Mild but Not Single Moderate Brain Trauma Is Associated with TAR DNA-Binding Protein 43 Mislocalization and Glial Activation in the Mouse …

T Janković, J Rajič Bumber, N Gržeta Krpan, P Dolenec… - Biomedicines, 2025 - mdpi.com
Background/Objectives: Traumatic brain injury (TBI) occurs after a sudden mechanical force
to the skull and represents a significant public health problem. Initial brain trauma triggers …

[HTML][HTML] Neuroprotective effect of triptolide on neuronal inflammation in rats with mild brain injury

Z Fang, G Shen, C Lou, BOA Botchway, Q Lu… - IBRO Neuroscience …, 2024 - Elsevier
Concussions sustained while playing sports are a prominent cause of mild traumatic brain
injury (mTBI), which is prevalent among teenagers. The early and intermediate stages of …

Differential expression patterns of TDP-43 in single moderate versus repetitive mild traumatic brain injury in mice

T Janković, P Dolenec, J Rajič Bumber… - International journal of …, 2021 - mdpi.com
Traumatic brain injury (TBI) is a disabling disorder and a major cause of death and disability
in the world. Both single and repetitive traumas affect the brain acutely but can also lead to …