Chiral molecules containing asymmetric carbon centers bonded with nitrogen are ubiquitous
in nature and also form important structural fragments in both natural and man-made …

Schiff base ligands are considered “privileged ligands” because they are easily prepared by
the condensation between aldehydes and imines. Stereogenic centres or other elements of …

Asymmetric multicomponent reactions involve the preparation of chiral compounds by the
reaction of three or more reagents added simultaneously. This kind of addition and reaction …

Chiral tertiary alcohols and R-tertiary amines are important building blocks of naturally
occurring and artificial biologically active molecules. Although there are catalytic asymmetric …

In the development of new systems for asymmetric synthesis it has always been a big
challenge to obtain optically active compounds with good yields and selectivities. For this …

Methods for enantioselective C–C bond constructions via additions to imines and related
compounds are reviewed, with an emphasis on the most recent efforts involving asymmetric …

The construction of chiral carbon centers via the first catalytic asymmetric alkynylation of
prochiral CH2 groups was developed by using a copper-catalyzed double activation of sp3 …

The development of syntheses providing enantiomerically pure α-amino acids has intrigued
generations of chemists and been the subject of intense research. This report describes a …

Tietze has defined a domino reaction as involving two or more bond-forming
transformations, which take place under the same reaction conditions, without adding …

The catalytic asymmetric addition reactions of organometallic reagents to CdN double bonds
of imines are fundamentally important processes, which provide convenient and versatile …