Respiratory pathogens such as influenza and SARS-CoV-2 can cause severe lung
infections leading to acute respiratory distress syndrome (ARDS). The pathophysiology of …

Progressive lung fibrosis is associated with poorly understood aging-related endothelial cell
dysfunction. To gain insight into endothelial cell alterations in lung fibrosis we performed …

The dynamic interactions between tumor endothelial cells (TECs) and the immune
microenvironment play a critical role in the progression of non-small cell lung cancer …

Reactivation and dysregulation of the mTOR signaling pathway are a hallmark of aging and
chronic lung disease; however, the impact on microvascular progenitor cells (MVPCs) …

Bone marrow endothelial cells (BM-ECs) are the essential components of the BM niche and
support the function of hematopoietic stem cells (HSCs). However, conditioning for HSC …

Vascular endothelial cell (EC) aging has a strong impact on tissue perfusion and overall
cardiovascular health. While studies confined to the investigation of aging-associated …

Pulmonary arterial hypertension (PAH) is a severe and lethal pulmonary vascular disease
characterized by arteriolar pruning and occlusive vascular remodeling leading to increased …

Systemic inflammatory response syndrome and respiratory distress syndrome can be
induced by lung injury caused by intestinal ischemia/reperfusion (II/R). There is no effective …

Lung endothelium resides at the interface between the circulation and the underlying tissue,
where it senses biochemical and mechanical properties of both the blood as it flows through …

Background: Severe acute respiratory syndrome (SARS) and acute respiratory distress
syndrome (ARDS) are often considered separate clinico-radiological entities. Whether these …