Oxidative stress has been implicated in the pathophysiology of diabetic nephropathy.
Studies in experimental animal models of diabetes strongly implicate oxidant species as a …

Endothelial dysfunction is characterized by a shift of the actions of the endothelium toward
reduced vasodilation, a proinflammatory state, and prothrombic properties. It is associated …

Obesity is increasing in prevalence worldwide and in all age groups. In nonpregnant
individuals, obesity is associated with dyslipidemia; hyperinsulinemia; vascular dysfunction; …

Obesity, insulin resistance, and endothelial dysfunction closely coexist throughout the
natural history of type 2 diabetes. They all can be identified not only in people with type 2 …

Aims/hypothesis To assess thiamine status by analysis of plasma, erythrocytes and urine in
type 1 and type 2 diabetic patients and links to markers of vascular dysfunction. Methods …

Although the biochemical steps linking insulin resistance with the metabolic syndrome have
not been completely clarified, mounting experimental and clinical evidence indicate …

Microvascular dysfunction (MVD) is considered a crucial pathway in the development and
progression of cardiometabolic and renal disease and is associated with increased …

Background: Obesity in pregnancy is increasing and is a risk factor for metabolic pathology
such as preeclampsia. In the nonpregnant, obesity is associated with dyslipidemia, vascular …

Diabetes mellitus and its complications are becoming one of the most important health
problems in the world. Diabetic nephropathy is now the main cause of end-stage renal …

Diabetes and its complications have become a public health problem. One of the most
important complications is diabetic nephropathy, which is nowadays the main cause of …