The emerging roles of ARID1A in tumor suppression
ARID1A has emerged as a tumor suppressor gene, which is mutated in a broad spectrum of
cancers, especially in those arising from ectopic or eutopic endometrium. As a subunit of …
cancers, especially in those arising from ectopic or eutopic endometrium. As a subunit of …
The emerging genomic landscape of endometrial cancer
M Le Gallo, DW Bell - Clinical chemistry, 2014 - academic.oup.com
BACKGROUND: Endometrial cancer is responsible for approximately 74 000 deaths
annually among women worldwide. It is a heterogeneous disease comprising multiple …
annually among women worldwide. It is a heterogeneous disease comprising multiple …
Loss of ARID1A expression and its relationship with PI3K-Akt pathway alterations, TP53 and microsatellite instability in endometrial cancer
T Bosse, NT Ter Haar, LM Seeber, FJ Hes… - Modern …, 2013 - nature.com
The switch/sucrose non-fermentable (SWI/SNF) subunit ARID1A (AT-rich interactive domain
1A gene) has been recently postulated as a novel tumor suppressor of gynecologic cancer …
1A gene) has been recently postulated as a novel tumor suppressor of gynecologic cancer …
[HTML][HTML] ARID1A loss correlates with mismatch repair deficiency and intact p53 expression in high-grade endometrial carcinomas
Abstract BAF250a (ARID1A) loss is a frequent event in high-grade endometrial cancers. It
has been proposed that ARID1A is a driver gene, with ARID1A mutations occurring …
has been proposed that ARID1A is a driver gene, with ARID1A mutations occurring …
ARID1A and CTNNB1/β-Catenin Molecular Status Affects the Clinicopathologic Features and Prognosis of Endometrial Carcinoma: Implications for an Improved …
A De Leo, D de Biase, J Lenzi, G Barbero, D Turchetti… - Cancers, 2021 - mdpi.com
Simple Summary Translation of the molecular characterization of endometrial cancer into
the clinical practice is emerging as a challenge. This study investigates the feasibility and …
the clinical practice is emerging as a challenge. This study investigates the feasibility and …
[HTML][HTML] Prognostic role and implications of mutation status of tumor suppressor gene ARID1A in cancer: a systematic review and meta-analysis
Loss of the tumor suppressor gene AT-rich interactive domain-containing protein 1A
(ARID1A) has been demonstrated in several cancers, but its prognostic role is unknown. We …
(ARID1A) has been demonstrated in several cancers, but its prognostic role is unknown. We …
ARID1A is essential for endometrial function during early pregnancy
AT-rich interactive domain 1A gene (ARID1A) loss is a frequent event in endometriosis-
associated ovarian carcinomas. Endometriosis is a disease in which tissue that normally …
associated ovarian carcinomas. Endometriosis is a disease in which tissue that normally …
[HTML][HTML] The clinicopathologic significance of p53 and BAF-250a (ARID1A) expression in clear cell carcinoma of the endometrium
TP53 mutation (and associated p53 protein overexpression) is probably a negative
prognostic marker in endometrial cancers, but its relevance in the rarer histologic subtypes …
prognostic marker in endometrial cancers, but its relevance in the rarer histologic subtypes …
Diagnostic significance and prognostic role of the ARID1A gene in cancer outcomes
EN Pavlidou, V Balis - World Academy of Sciences …, 2020 - spandidos-publications.com
Mutations of the ARID1A gene, which encodes the basic directional subunit of SWI/SNF
chromatin remodeling complexes, were detected in the middle of the last decade in several …
chromatin remodeling complexes, were detected in the middle of the last decade in several …
CCNE1 amplification is associated with aggressive potential in endometrioid endometrial carcinomas
K Nakayama, MT Rahman… - International …, 2015 - spandidos-publications.com
The clinicopathological significance of amplification was investigated of the gene encoding
cyclin E (CCNE1) and we assessed whether CCNE1 was a potential target in endometrioid …
cyclin E (CCNE1) and we assessed whether CCNE1 was a potential target in endometrioid …