Human papillomaviruses (HPV) are a large family of viruses which contain a circular, double-
stranded DNA genome of approximately 8000 base pairs. The viral DNA is chromatinized by …

Epstein-Barr virus (EBV) is a model of herpesvirus latency and epigenetic changes. The
virus preferentially infects human B-lymphocytes (and also other cell types) but does not turn …

Viral latency can be considered a metastable, nonproductive infection state that is capable
of subsequent reactivation to repeat the infection cycle. Viral latent infections have …

Abstract Background Transposable elements (TEs) make up half of mammalian genomes
and shape genome regulation by harboring binding sites for regulatory factors. These …

The complex life cycle of oncogenic human papillomavirus (HPV) initiates in undifferentiated
basal epithelial keratinocytes where expression of the E6 and E7 oncogenes is restricted …

Viruses have long been viewed as entities possessing extremely limited metabolic
capacities. Over the last decade, however, this view has been challenged, as metabolic …

It is increasingly clear that DNA viruses exploit cellular epigenetic processes to control their
life cycles during infection. This review will address epigenetic regulation in members of the …

Human cytomegalovirus (HCMV) is a prevalent pathogen that establishes life-long latent
infection in hematopoietic cells. While this infection is usually asymptomatic, immune …

During a long history of coevolution, herpesviruses have reached a fine-tuned balance with
their hosts, allowing them to successfully persist and spread to new hosts without causing …

Viral DNA genomes replicating in cells encounter a myriad of host factors that facilitate or
hinder viral replication. Viral proteins expressed early during infection modulate host factors …