Uropathogenic Escherichia coli (UPEC)-Associated Urinary Tract Infections: The Molecular Basis for Challenges to Effective Treatment

S Whelan, B Lucey, K Finn - Microorganisms, 2023 - mdpi.com
Urinary tract infections (UTIs) are among the most common bacterial infections, especially
among women and older adults, leading to a significant global healthcare cost burden …

Nitrate water contamination from industrial activities and complete denitrification as a remediation option

KM Moloantoa, ZP Khetsha, E Van Heerden… - Water, 2022 - mdpi.com
Freshwater is a scarce resource that continues to be at high risk of pollution from
anthropogenic activities, requiring remediation in such cases for its continuous use. The …

Bacterial biofilms in the human body: Prevalence and impacts on health and disease

EK Perry, MW Tan - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
Bacterial biofilms can be found in most environments on our planet, and the human body is
no exception. Consisting of microbial cells encased in a matrix of extracellular polymers …

Respiration-induced biofilm formation as a driver for bacterial niche colonization

AJ Martín-Rodríguez - Trends in Microbiology, 2023 - cell.com
Depending on their physiology and metabolism, bacteria can carry out diverse redox
processes for energy acquisition, which facilitates adaptation to environmental or host …

Molybdenum enzymes and how they support virulence in pathogenic bacteria

Q Zhong, B Kobe, U Kappler - Frontiers in Microbiology, 2020 - frontiersin.org
Mononuclear molybdoenzymes are highly versatile catalysts that occur in organisms in all
domains of life, where they mediate essential cellular functions such as energy generation …

Two-component systems regulate bacterial virulence in response to the host gastrointestinal environment and metabolic cues

C Shaw, M Hess, BC Weimer - Virulence, 2022 - Taylor & Francis
Two-component systems are ubiquitous signaling mechanisms in bacteria that enable
intracellular changes from extracellular cues. These bacterial regulatory systems couple …

Recurrent urinary tract infections: unraveling the complicated environment of uncomplicated rUTIs

J Josephs-Spaulding, TJ Krogh, HC Rettig… - Frontiers in cellular …, 2021 - frontiersin.org
Urinary tract infections (UTIs) are frequent in humans, affecting the upper and lower urinary
tract. Present diagnosis relies on the positive culture of uropathogenic bacteria from urine …

Role of metabolism in uropathogenic Escherichia coli

CCY Chan, IA Lewis - Trends in Microbiology, 2022 - cell.com
Uropathogenic Escherichia coli (UPEC) is responsible for more than 75% of urinary tract
infections (UTIs) and has been studied extensively to better understand the molecular …

Nitrate is an environmental cue in the gut for Salmonella enterica serovar typhimurium biofilm dispersal through curli repression and flagellum activation via cyclic-di …

AL Miller, LK Nicastro, S Bessho, K Grando, AP White… - Mbio, 2022 - Am Soc Microbiol
Curli, a major component of the bacterial biofilms in the intestinal tract, activates pattern
recognition receptors and triggers joint inflammation after infection with Salmonella enterica …

Isolation and Characterization of vB_kpnM_17-11, a Novel Phage Efficient Against Carbapenem-Resistant Klebsiella pneumoniae

J Bai, F Zhang, S Liang, Q Chen, W Wang… - Frontiers in cellular …, 2022 - frontiersin.org
Phages and phage-encoded proteins exhibit promising prospects in the treatment of
Carbapenem-Resistant Klebsiella pneumoniae (CRKP) infections. In this study, a novel …