Primary Sjögren syndrome (pSS) is a progressive autoimmune disease characterized by
sicca and systemic manifestations. In this Review, we summarize the available data on …

Several lines of evidence support a role of the immune system in headache pathogenesis,
with particular regard to migraine. Firstly, alterations in cytokine profile and in lymphocyte …

There is currently no approved treatment for primary Sjögren's syndrome, a disease that
primarily affects adult women. The difficulty in developing effective therapies is-in part …

Objective: Sjögren's syndrome is a heterogeneous inflammatory disorder frequently
involving peripheral nerves with a wide spectrum of sensory modalities and distribution …

OBJECTIVES: To analyse the frequency and characterise the systemic presentation of
primary Sjögren's syndrome (SS) out of the ESSDAI classification in a large international …

Unlike conventional itch, neuropathic itch develops in normal skin from excess peripheral
firing or dampened central inhibition of itch pathway neurons. Neuropathic itch is a symptom …

Abstract Objective Neurological manifestations of Sjögren's syndrome can be severe but
also treatment-responsive. We aimed to systematically evaluate neurological manifestations …

Objective To identify the principal determinants of health‐related quality of life (HRQOL)
impairment in patients with active primary Sjögren's syndrome (SS) participating in a large …

Objectives Onset of primary SS is usually between 40 and 60 years of age, with severe
systemic complications in 15% of cases. We sought to determine whether early-onset …

Extraglandular manifestations (EGMs) in primary Sjogren's syndrome (pSS) represent the
clinical expression of the systemic involvement in this disease. EGMs are characterized by a …