Control of breathing and the circulation in high-altitude mammals and birds
Hypoxia is an unremitting stressor at high altitudes that places a premium on oxygen
transport by the respiratory and cardiovascular systems. Phenotypic plasticity and genotypic …
transport by the respiratory and cardiovascular systems. Phenotypic plasticity and genotypic …
Control of breathing and ventilatory acclimatization to hypoxia in deer mice native to high altitudes
Aim We compared the control of breathing and heart rate by hypoxia between high‐and low‐
altitude populations of Peromyscus mice, to help elucidate the physiological specializations …
altitude populations of Peromyscus mice, to help elucidate the physiological specializations …
Ventilatory acclimatization to hypoxia in mice: methodological considerations
We examined ventilatory acclimatization to hypoxia (VAH) in CD1 mice, and contrasted
results obtained using the barometric method on unrestrained mice with …
results obtained using the barometric method on unrestrained mice with …
Long-term ventilatory adaptation and ventilatory response to hypoxia in plateau pika (Ochotona curzoniae): role of nNOS and dopamine
We assessed ventilatory patterns and ventilatory responses to hypoxia (HVR) in high-
altitude (HA) plateau pikas, repetitively exposed to hypoxic burrows, and control rats. We …
altitude (HA) plateau pikas, repetitively exposed to hypoxic burrows, and control rats. We …
Gene regulatory changes underlie developmental plasticity in respiration and aerobic performance in highland deer mice
Phenotypic plasticity can play an important role in the ability of animals to tolerate
environmental stress, but the nature and magnitude of plastic responses are often specific to …
environmental stress, but the nature and magnitude of plastic responses are often specific to …
Guinea pig oxygen-sensing and carotid body functional properties
E Gonzalez-Obeso, I Docio, E Olea… - Frontiers in …, 2017 - frontiersin.org
Mammals have developed different mechanisms to maintain oxygen supply to cells in
response to hypoxia. One of those mechanisms, the carotid body (CB) chemoreceptors, is …
response to hypoxia. One of those mechanisms, the carotid body (CB) chemoreceptors, is …
Effects of cigarette smoke and chronic hypoxia on airways remodeling and resistance. Clinical significance
E Olea, E Ferrer, J Prieto-Lloret… - Respiratory physiology …, 2011 - Elsevier
Previously we have reported that association of cigarette smoke (CS) and chronic hypoxia
(CH) interact positively to physiopathologically remodel pulmonary circulation. In present …
(CH) interact positively to physiopathologically remodel pulmonary circulation. In present …
Are the carotid bodies of the guinea-pig functional?
DO Schwenke, CP Bolter, PA Cragg - … and Physiology Part A: Molecular & …, 2007 - Elsevier
We have previously observed that the guinea-pig appears to have a relatively poor
ventilatory (V̇E) response to hypoxia, compared to other mammals. Therefore, in this study …
ventilatory (V̇E) response to hypoxia, compared to other mammals. Therefore, in this study …
Life-long exposure to hypoxia affects metabolism and respiratory physiology across life stages in high-altitude deer mice (Peromyscus maniculatus)
Hypoxia exposure can have distinct physiological effects between early developmental and
adult life stages, but it is unclear how the effects of hypoxia may progress during continuous …
adult life stages, but it is unclear how the effects of hypoxia may progress during continuous …
Alveolar diffusion-perfusion interactions during high-altitude residence in guinea pigs
C Yilmaz, D Merrill Dane… - Journal of applied …, 2007 - journals.physiology.org
We previously reported in weanling guinea pigs raised at high altitude (HA; 3,800 m) an
elevated lung diffusing capacity estimated by morphometry from alveolar-capillary surface …
elevated lung diffusing capacity estimated by morphometry from alveolar-capillary surface …