Diabetic encephalopathies are now accepted complications of diabetes. They appear to
differ in type 1 and type 2 diabetes as to underlying mechanisms and the nature of resulting …

Apoptosis mediates the precise and programmed natural death of neurons and is a
physiologically important process in neurogenesis during maturation of the central nervous …

Serum starvation is one of the most frequently performed procedures in molecular biology
and there are literally thousands of research papers reporting its use. In fact, this method has …

The understanding of the epidemiology of diabetic peripheral neuropathy has been made
difficult by methodological issues relating to many of the published studies. Inconsistency in …

Diabetes is an increasingly common disorder which causes and contributes to a variety of
central nervous system (CNS) complications which are often associated with cognitive …

Connecting Peptide, or C-peptide, is a product of the insulin prohormone, and is released
with and in amounts equimolar to those of insulin. While it was once thought that C-peptide …

It is well known that C-peptide fulfills an important function in the synthesis of insulin. After
cleavage of proinsulin in the pancreatic b-cells, the 31-amino acid C-peptide is secreted into …

Primary diabetic encephalopathy is a recently recognized late complication of diabetes
resulting in a progressive decline in cognitive faculties. In the spontaneously type 1 diabetic …

Over recent decades, the development of specialised techniques such as patch clamping
and site-directed mutagenesis have established the contribution of neuronal ion channel …

Worldwide, diabetes and its complications have seriously affected people's quality of life and
become a serious public health problem. C-peptide is not only an indicator of pancreatic β …