Anderson-Fabry disease (AFD) is an X-linked lysosomal storage disorder caused by
deficient activity of the enzyme alpha-galactosidase. While AFD is recognized as a …

The treatment landscape for lysosomal storage disorders (LSDs) is rapidly evolving. An
increase in the number of preclinical and clinical studies in the last decade has …

Fabry disease (FD) is a lysosomal storage disorder due to the impaired activity of the α-
galactosidase A (GLA) enzyme which induces Gb3 deposition and multiorgan dysfunction …

Background: Fabry cardiomyopathy is characterized by left ventricular hypertrophy,
myocardial fibrosis, arrhythmia, and premature death. Treatment with migalastat, an oral …

Echocardiographic differentiation of cardiac amyloidosis (CA) and Fabry disease (FD) is
often challenging using standard echocardiographic parameters. We retrospectively …

Fabry disease (FD) is a rare, X-linked lysosomal storage disorder affecting both males and
females caused by genetic abnormalities in the gene encoding the enzyme α-galactosidase …

Heart failure with preserved ejection fraction (HFpEF) traditionally has been characterized
as a form of heart failure without therapeutic options, in particular with a lack of response to …

Anderson-Fabry disease (AFD) is a rare multisystem X-linked lysosomal storage disorder
caused by α-galactosidase A enzyme deficiency. Long-term cardiac involvement in AFD …

One of the main causes of heart failure is cardiomyopathies. Among them, the most common
is hypertrophic cardiomyopathy (HCM), characterized by thickening of the left ventricular …

Background: Fabry disease (FD) is a multisystem, monogenic, X-linked storage disorder
caused by mutations in the GLA gene, resulting in reduced alfa-galactosidase A enzyme …