Iron oxide nanoparticles in regenerative medicine and tissue engineering

RP Friedrich, I Cicha, C Alexiou - Nanomaterials, 2021 - mdpi.com
In recent years, many promising nanotechnological approaches to biomedical research
have been developed in order to increase implementation of regenerative medicine and …

[HTML][HTML] Force: A messenger of axon outgrowth

V Raffa - Seminars in Cell & Developmental Biology, 2023 - Elsevier
The axon is a sophisticated macromolecular machine composed of interrelated parts that
transmit signals like spur gears transfer motion between parallel shafts. The growth cone is a …

Assessing the combination of magnetic field stimulation, iron oxide nanoparticles, and aligned electrospun fibers for promoting neurite outgrowth from dorsal root …

JL Funnell, AM Ziemba, JF Nowak, H Awada… - Acta biomaterialia, 2021 - Elsevier
Magnetic fiber composites combining superparamagnetic iron oxide nanoparticles (SPIONs)
and electrospun fibers have shown promise in tissue engineering fields. Controlled grafting …

Extremely low forces induce extreme axon growth

S De Vincentiis, A Falconieri, M Mainardi… - Journal of …, 2020 - Soc Neuroscience
Stretch-growth has been defined as a process that extends axons via the application of
mechanical forces. In the present article, we used a protocol based on magnetic …

Low forces push the maturation of neural precursors into neurons

S De Vincentiis, M Baggiani, F Merighi, V Cappello… - Small, 2023 - Wiley Online Library
Mechanical stimulation modulates neural development and neuronal activity. In a previous
study, magnetic “nano‐pulling” is proposed as a tool to generate active forces. By loading …

External magnetic field non-invasively stimulates spinal cord regeneration in rat via a magnetic-responsive aligned fibrin hydrogel

CY Yang, Z Meng, K Yang, Z He, Z Hou, J Yang… - …, 2023 - iopscience.iop.org
Magnetic stimulation is becoming an attractive approach to promote neuroprotection,
neurogenesis, axonal regeneration, and functional recovery in both the central nervous …

Magnetic composite biomaterials for neural regeneration

JL Funnell, B Balouch, RJ Gilbert - Frontiers in Bioengineering and …, 2019 - frontiersin.org
Nervous system damage caused by physical trauma or degenerative diseases can result in
loss of sensory and motor function for patients. Biomaterial interventions have shown …

A novel magnetic manipulation promotes directional growth of periodontal ligament stem cells

W Li, W Tian, Y Wu, S Guo - Tissue Engineering Part A, 2023 - liebertpub.com
Periodontium is the rally of soft and hard tissues, which will be devastated continuously by
the compromise of periodontitis. Current periodontal therapeutic methods cannot effectively …

Cellular and molecular processes are differently influenced in primary neural cells by slight changes in the physicochemical properties of multicore magnetic …

E Benayas, A Espinosa, MT Portolés… - … Applied Materials & …, 2023 - ACS Publications
Herein, we use two exemplary superparamagnetic iron oxide multicore nanoparticles
(SPIONs) to illustrate the significant influence of slightly different physicochemical properties …

Force-mediating magnetic nanoparticles to engineer neuronal cell function

TJ Gahl, A Kunze - Frontiers in Neuroscience, 2018 - frontiersin.org
Cellular processes like membrane deformation, cell migration, and transport of organelles
are sensitive to mechanical forces. Technically, these cellular processes can be …