Twenty years ago, a number of eminent pharmaceutical scientists collaborated on an article
describing a rational approach to developing stable lyophilized protein formulations …

Dextran 70 and its building block (glucose) has been used as macromolecular crowder and
osmolyte, respectively. The difference in size and structure of both made us inquisitive to …

Living cells are crowded. The presence of so many macromolecules packed into a confined
environment affects the structure and function of biological components, and the kinetics and …

The thermal stability of apo α–lactalbumin (α–LA) and lysozyme was measured in the
presence of mixtures of glucose, fructose, and galactose. Mixtures of these …

In order to better understand how the complex, densely packed, heterogeneous milieu of a
cell influences enzyme kinetics, we exposed opposing reactions catalyzed by yeast alcohol …

Small-molecule crosslinkers could diffuse into and stabilize protein hydrogels without
damaging their appearance, but they are absent from the food industry due to the high safety …

The current study focuses on the experimental evidence to describe the molecular
mechanism by which the sugars modulate the thermodynamic stability of hen egg-white …

Catalase is an important antioxidant enzyme that catalyzes the disproportionation of H2O2
into harmless water and molecular oxygen. Due to various applications of the enzyme in …

Since its inception, food additive has been an integral part of the food processing industry
with various commercial roles. Besides its advantages, various studies have already …

Guanidine hydrochloride (GdnHCl) and thermal denaturation studies on lysozyme were
made in the absence and the presence of a simulated honey sugar cocktail (SHSC) …