Punica granatum (pomegranate) and its potential for prevention and treatment of inflammation and cancer

EP Lansky, RA Newman - Journal of ethnopharmacology, 2007 - Elsevier
The last 7 years have seen over seven times as many publications indexed by Medline
dealing with pomegranate and Punica granatum than in all the years preceding them …

Natural and synthetic antioxidants: an updated overview

A Augustyniak, G Bartosz, A Čipak, G Duburs… - Free radical …, 2010 - Taylor & Francis
The current understanding of the complex role of ROS in the organism and pathological
sequelae of oxidative stress points to the necessity of comprehensive studies of antioxidant …

Incorporating selenium into heterocycles and natural products─ from chemical properties to pharmacological activities

W Hou, H Xu - Journal of Medicinal Chemistry, 2022 - ACS Publications
Selenium (Se)-containing compounds have emerged as potential therapeutic agents for the
treatment of a range of diseases. Through tremendous effort, considerable knowledge has …

Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer

AJ Pantuck, JT Leppert, N Zomorodian, W Aronson… - Clinical Cancer …, 2006 - AACR
Purpose: Phytochemicals in plants may have cancer preventive benefits through
antioxidation and via gene-nutrient interactions. We sought to determine the effects of …

[PDF][PDF] Bioactive chemical constituents from pomegranate (Punica granatum) juice, seed and peel-a review

CVS Prakash, I Prakash - … Journal of Research in Chemistry and …, 2011 - academia.edu
The pomegranate tree, Punica granatum possesses a vast ethnomedical history and
represents a phytochemical reservoir of heuristic medicinal value. The pomegranate tree …

Tocotrienols: the emerging face of natural vitamin E

CK Sen, S Khanna, C Rink, S Roy - Vitamins & Hormones, 2007 - Elsevier
Natural vitamin E includes eight chemically distinct molecules: α‐, β‐, γ‐, and δ‐tocopherols
and α‐, β‐, γ‐, and δ‐tocotrienols. More than 95% of all studies on vitamin E are directed …

Discovery of novel bicyclic phenylselenyl-containing hybrids: an orally bioavailable, potential, and multiacting class of estrogen receptor modulators against endocrine …

X Deng, B Xie, Q Li, Y Xiao, Z Hu, X Deng… - Journal of Medicinal …, 2022 - ACS Publications
Breast cancer (BC) is a multifactorial disease and is prone to drug resistance during
treatment. In this study, we described a new class of multifunctional estrogen receptor (ER) …

γ-Tocotrienol suppresses prostate cancer cell proliferation and invasion through multiple-signalling pathways

WN Yap, PN Chang, HY Han, DTW Lee, MT Ling… - British journal of …, 2008 - nature.com
Tocotrienol-rich fraction (TRF) has demonstrated antiproliferative effect on prostate cancer
(PCa) cells. To elucidate this anticancer property in PCa cells, this study aimed, first, to …

Vitamin E analogs, a novel group of “mitocans,” as anticancer agents: the importance of being redox-silent

J Neuzil, M Tomasetti, Y Zhao, LF Dong… - Molecular …, 2007 - ASPET
The search for a selective and efficient anticancer agent for treating all neoplastic disease
has yet to deliver a universally suitable compound (s). The majority of established anticancer …

Direct biocatalysed synthesis of first sulfur-, selenium-and tellurium-containing l-ascorbyl hybrid derivatives with radical trapping and GPx-like properties

D Tanini, B Lupori, G Malevolti, M Ambrosi… - Chemical …, 2019 - pubs.rsc.org
6-OL-Ascorbyl selenoesters, thioesters and telluroesters can be efficiently and directly
prepared from L-ascorbic acid and suitable functionalised chalcogenoesters through lipase …