Context.—Controversies and uncertainty persist in prostate cancer grading. Objective.—To
update grading recommendations. Data Sources.—Critical review of the literature along with …

The definition of clinically significant prostate cancer is a dynamic process that was initiated
many decades ago, when there was already evidence that a great proportion of patients with …

Five years after the last prostatic carcinoma grading consensus conference of the
International Society of Urological Pathology (ISUP), accrual of new data and modification of …

Hyperpolarised magnetic resonance imaging (HP 13C-MRI) is an emerging clinical
technique to detect [1-13C] lactate production in prostate cancer (PCa) following intravenous …

Relative increase of grade 4 and presence of invasive cribriform and/or intraductal
carcinoma have individually been associated with adverse outcome of Gleason score 7 (GS …

Gleason grading of histological images is important in risk assessment and treatment
planning for prostate cancer patients. Much research has been done in classifying small …

Data from the past 6 years have shown that the presence of any amount of cribriform (or
more comprehensively, large acinar cribriform to papillary) pattern of invasive prostate …

Purpose: To our knowledge the ideal methodology of quantifying secondary Gleason pattern
4 in men with Grade Group 2/Gleason score 3+ 4= 7 on biopsy remains unknown. We …

Purpose: Accurate risk stratification remains a barrier for the safety of active surveillance in
patients with intermediate-risk prostate cancer.[68Ga] Ga-PSMA-11 prostate-specific …

The management of newly diagnosed prostate cancer is challenging because of its
heterogeneity in histology, genetics and clinical outcome. The clinical outcome of patients …