Challenges and recent progress in oral drug delivery systems for biopharmaceuticals

B Homayun, X Lin, HJ Choi - Pharmaceutics, 2019 - mdpi.com
Routes of drug administration and the corresponding physicochemical characteristics of a
given route play significant roles in therapeutic efficacy and short term/long term biological …

Oral drug delivery platforms for biomedical applications

J Ouyang, Z Zhang, B Deng, J Liu, L Wang, H Liu… - Materials Today, 2023 - Elsevier
Oral administration is perhaps the most commonly used and acceptable route for drug
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …

[HTML][HTML] Microfluidic electrospray niacin metal-organic frameworks encapsulated microcapsules for wound healing

G Chen, Y Yu, X Wu, G Wang, G Gu, F Wang, J Ren… - Research, 2019 - spj.science.org
Niacin metal-organic frameworks (MOFs) encapsulated microcapsules with alginate shells
and copper-/zinc-niacin framework cores were in situ synthesized by using a microfluidic …

Implication of nano-antioxidant therapy for treatment of hepatocellular carcinoma using PLGA nanoparticles of rutin

P Pandey, M Rahman, PC Bhatt, S Beg, B Paul… - …, 2018 - Taylor & Francis
Aim: The present work describes the development of poly (lactic co-glycolic acid)(PLGA)
nanoparticles (NPs) of rutin (RT) for the treatment of hepatocellular carcinoma in rats …

Micropathological chip modeling the neurovascular unit response to inflammatory bone condition

E Neto, AC Monteiro, C Leite Pereira… - Advanced …, 2022 - Wiley Online Library
Organ‐on‐a‐chip in vitro platforms accurately mimic complex microenvironments offering
the ability to recapitulate and dissect mechanisms of physiological and pathological settings …

[HTML][HTML] Role of nanostructures in improvising oral medicine

S Ghosh, S Ghosh, PC Sil - Toxicology Reports, 2019 - Elsevier
The most preferable mode of drugs administration is via the oral route but physiological
barriers such as pH, enzymatic degradation etc. limit the absolute use of this route. Herein …

Ganoderic acid loaded nano-lipidic carriers improvise treatment of hepatocellular carcinoma

M Rahman, SA Al-Ghamdi, KS Alharbi, S Beg… - Drug Delivery, 2019 - Taylor & Francis
This work evaluates nano-lipid carrier of ganoderic acid (GA) and molecular docking on
various cancer signaling pathways, an attempt to improve the hepatic condition associated …

[HTML][HTML] Transdermal delivery of IBU-PLGA nanoparticles with dissolving microneedle array patch

F Yang, W Wang, J Zhou, Z Yu, M An, W He… - Journal of Drug Delivery …, 2024 - Elsevier
There are few systematic studies using microneedles to deliver ibuprofen through the skin.
In this study, Ibuprofen was encapsulated in poly (lactide-co-Glycolide)(PLGA) network to …

Green pH-and magnetic-responsive hybrid hydrogels based on poly (methacrylic acid) and Eucalyptus wood nanocellulose for controlled release of ibuprofen

MD Markovic, SI Seslija, VD Ugrinovic, M Kunaver… - Cellulose, 2021 - Springer
Abstract pH-and magnetic-sensitive hybrid hydrogels based on poly (methacrylic
acid)(PMAA), nanocellulose (NC), carboxymethyl cellulose (CMC) and magnetite particles …

ROS-responsive copolymer micelles for inflammation triggered delivery of ibuprofen

JY Quek, R Bright, PRL Dabare, K Vasilev - Colloids and Surfaces B …, 2022 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used for the treatment of
pain, inflammation and fever. However, most NSAIDs are poorly water soluble, making it …