The emerging role of autophagy as a target of environmental pollutants: an update on mechanisms
Autophagy is an evolutionarily conserved cellular system crucial for cellular homeostasis
that protects cells from a broad range of internal and extracellular stresses. Autophagy …
that protects cells from a broad range of internal and extracellular stresses. Autophagy …
MitoNEET preserves muscle insulin sensitivity during iron overload by regulating mitochondrial iron, reactive oxygen species and fission
E Tam, K Nguyen, HK Sung, G Sweeney - The FEBS Journal, 2024 - Wiley Online Library
Iron overload (IO) is known to contribute to metabolic dysfunctions such as type 2 diabetes
and insulin resistance. Using L6 skeletal muscle cells overexpressing the CDGSH iron …
and insulin resistance. Using L6 skeletal muscle cells overexpressing the CDGSH iron …
[HTML][HTML] Autophagy deficiency exacerbated hypoxia-reoxygenation induced inflammation and cell death via a mitochondrial DNA/STING/IRF3 pathway
Aims Autophagy is an important cellular process for maintaining physiological homeostasis
and is known to protect against cardiovascular diseases including ischemia reperfusion (I/R) …
and is known to protect against cardiovascular diseases including ischemia reperfusion (I/R) …
Contribution of Autophagy to Cellular Iron Homeostasis and Stress Adaptation in Alternaria alternata
The tangerine pathotype of Alternaria alternata produces the Alternaria citri toxin (ACT),
which elicits a host immune response characterized by the increase in harmful reactive …
which elicits a host immune response characterized by the increase in harmful reactive …
[HTML][HTML] Cardioprotective Effects of Adiponectin-Stimulated Autophagy
E Tam, M Ouimet, G Sweeney - Journal of Lipid and Atherosclerosis, 2025 - e-jla.org
Cardiovascular diseases (CVDs), including heart failure, pose a significant economic and
health burden worldwide. Current treatment strategies for heart failure are greatly limited, in …
health burden worldwide. Current treatment strategies for heart failure are greatly limited, in …