Across complex, multi-time and-length scale biological systems, redundancy confers
robustness and resilience, enabling adaptation and increasing survival under dynamic …

Stem cells are considered the fundamental underpinnings of tissue biology. The stem cell
microenvironment provides factors and elements that play significant roles in controlling the …

Human pluripotent stem cell (hPSC)-derived endothelial cells and their progenitors may
provide the means for vascularization of tissue-engineered constructs and can serve as …

Stem cells interpret signals from their microenvironment while simultaneously modifying the
niche through secreting factors and exerting mechanical forces. Many soluble stem cell cues …

Stem‐cell‐based therapies have the potential to provide novel solutions for the treatment of
a variety of diseases, but the main obstacles to such therapies lie in the uncontrolled …

Anchorage-dependent cells are of great interest for various biotechnological applications.(i)
They represent a formidable production means of viruses for vaccination purposes at very …

In recent years, our scientific interest in spaceflight has grown exponentially and resulted in
a thriving area of research, with hundreds of astronauts spending months of their time in …

Retinal degeneration is a leading cause of vision impairment and blindness worldwide and
medical care for advanced disease does not exist. Stem cell-derived retinal organoids …

The ability to develop cost‐effective, scalable and robust bioprocesses for human pluripotent
stem cells (hPSCs) will be key to their commercial success as cell therapies and tools for …

Stem cells play essential roles in tissue regeneration in vivo via specific lineage
differentiation induced by environmental factors. In the past, biochemical signals were the …