The role of AMPK in cancer metabolism and its impact on the immunomodulation of the tumor microenvironment

CK Keerthana, TP Rayginia, SC Shifana… - Frontiers in …, 2023 - frontiersin.org
Adenosine monophosphate-activated protein kinase (AMPK) is a key metabolic sensor that
is pivotal for the maintenance of cellular energy homeostasis. AMPK contributes to diverse …

[HTML][HTML] Biological activities of curcuminoids, other biomolecules from turmeric and their derivatives–A review

A Amalraj, A Pius, S Gopi, S Gopi - Journal of traditional and …, 2017 - Elsevier
In recent years, several drugs have been developed deriving from traditional products and
current drug research is actively investigating the possible therapeutic roles of many …

The anti-inflammatory and immunomodulatory activities of natural products to control autoimmune inflammation

KD Moudgil, SH Venkatesha - International journal of molecular sciences, 2022 - mdpi.com
Inflammation is an integral part of autoimmune diseases, which are caused by dysregulation
of the immune system. This dysregulation involves an imbalance between pro-inflammatory …

Curcumin and diabetes: a systematic review

D Zhang, M Fu, SH Gao, JL Liu - … ‐Based Complementary and …, 2013 - Wiley Online Library
Turmeric (Curcuma longa), a rhizomatous herbaceous perennial plant of the ginger family,
has been used for the treatment of diabetes in Ayurvedic and traditional Chinese medicine …

AMPK activators: mechanisms of action and physiological activities

J Kim, G Yang, Y Kim, J Kim, J Ha - Experimental & molecular medicine, 2016 - nature.com
AMP-activated protein kinase (AMPK) is a central regulator of energy homeostasis, which
coordinates metabolic pathways and thus balances nutrient supply with energy demand …

Targeting AMPK by statins: a potential therapeutic approach

S Dehnavi, A Kiani, M Sadeghi, AF Biregani, M Banach… - Drugs, 2021 - Springer
Statins are a group of lipid-lowering drugs that inhibit cholesterol biosynthesis and have anti-
inflammatory, anti-tumor, and immunomodulatory properties. Several lines of evidence …

[HTML][HTML] Polyphenols and their effects on diabetes management: A review

N Aryaeian, SK Sedehi, T Arablou - … of the Islamic Republic of Iran, 2017 - ncbi.nlm.nih.gov
Background: Type 2 diabetes is a growing public health problem and is associated with
increased morbidity and mortality. The worldwide prevalence of type 2 diabetes is rising …

[PDF][PDF] Curcumin and its derivatives: A review of their biological activities

MK Oglah, YF Mustafa, MK Bashir, MH Jasim… - Syst. Rev …, 2020 - researchgate.net
Since the dawn of humankind, natural products have been widely used as a medicine for the
management of a wide range of diseases that affected the human health (1). Natural product …

Diabetes is an inflammatory disease: evidence from traditional Chinese medicines

W Xie, L Du - Diabetes, obesity and metabolism, 2011 - Wiley Online Library
Diabetes is usually associated with inflammation. Inflammation contributes to the
development of diabetes. Traditional Chinese medicines (TCM) play an important role in …

Curcumin: a natural product for diabetes and its complications

S Fazel Nabavi, R Thiagarajan… - Current topics in …, 2015 - ingentaconnect.com
Curcumin is the yellow-colored bioactive constituent of the perennial plant, Curcuma longa
L., which possesses a wide range of physiological and pharmacological properties such as …