Sex characteristics exhibit significant disparities in various human diseases, including
prevalent cardiovascular diseases, cancers, metabolic disorders, autoimmune diseases …

Nerve growth factor (NGF) was the first neurotrophin described. This neurotrophin
contributes to organogenesis by promoting sensory innervation and angiogenesis in the …

Sexual dimorphism in energy metabolism is now established and suggested to affect many
aspects of metabolic diseases, and-in particular-diabetes, and obesity. This is strongly …

Gestational diabetes (GDM) changes the maternal metabolic and uterine environment, thus
increasing the risk of short-and long-term adverse outcomes for both mother and child …

Background Some phenotypical changes may be related to changes in the associations
among genes. The set of such associations is referred to as gene interaction (or association) …

Prenatal stress may lead to tissue-and sex-specific cardiometabolic disorders in the
offspring through imbalances in the insulin signaling pathway. Therefore, we aimed to …

Simple Summary Obesity is highly associated with overall risk for breast cancer and
correlated with aggressive behavior. Although recent advances indicated that increased BMI …

Background Insulin resistance (IR) is a condition in which the response of organs to insulin
is impaired. IR is an early marker of metabolic dysfunction. However, IR also appears in …

Tissue microenvironments are rich in signaling molecules. However, factors in the tissue
matrix that can serve as tissue-specific cues for engineering pancreatic tissues have not …

Cardiovascular diseases (CVDs) are the leading cause of mortality and disability among
both males and females. The risk of cardiovascular diseases is heightened by the presence …