Allergen immunotherapy (IT) is a proven approach for treating allergic rhinitis and allergic
asthma that has been practiced since 1911 and has undergone significant development in …

The highlighted mechanisms may not only contribute to improved specific immunotherapy,
but also give insight into a clinically relevant therapy targeting regulatory T cells. The …

Background: Despite the well-documented efficacy of Hymenoptera specific immunotherapy
(SIT), there is no safe method to reliably characterise the patient level of protection. Only …

CD86 is a well-known costimulatory molecule in its interaction with CD28 and/or CTLA
present on T cells, and is essential for full activation of naive T-cell and subsequent …

Introduction. T cell receptor excision circles (TREC) on CD31+ T cells are related to recent
thymic emigrant cells (RTEs). The involvement of the functional thymic tissue occurs early in …

Despite the current knowledge, the mechanisms by which the specific immunotherapy (SIT)
achieves clinical improvement remains unclear. However, it is now clear that the immune …

Local climate changes can impact on a number of factors, including air pollution, that have
been shown to influence both the development and attacks of allergic respiratory diseases …

Introdução: Os círculos de excisão do receptor da célula T (TRECs) em linfócitos T-CD31+
correlacionam-se com células recentemente emigradas do timo (RTEs). Objectivo: Avaliar o …

Anotace Dendritické buňky jsou nejdůležitější antigen prezentující buňky, které stimulují
naivní T a B buňky a regulují tak imunitní odpověď organizmu. Jsou rozmístěny téměř ve …

Local climate changes can impact on a number of factors, including air pollution, that have
been shown to influence both the development and attacks of allergic respiratory diseases …