A Frutiger, A Tanno, S Hwu, RF Tiefenauer… - Chemical …, 2021 - ACS Publications
Nature achieves differentiation of specific and nonspecific binding in molecular interactions through precise control of biomolecules in space and time. Artificial systems such as …
W Timp, G Timp - Science Advances, 2020 - science.org
Proteins can be the root cause of a disease, and they can be used to cure it. The need to identify these critical actors was recognized early (1951) by Sanger; the first biopolymer …
Nanopores are single-molecule sensors used in nucleic acid analysis, whereas their applicability towards full protein identification has yet to be demonstrated. Here, we show …
L Wen, Y Tian, L Jiang - Angewandte Chemie International …, 2015 - Wiley Online Library
Engineered wettability is a traditional, yet key issue in surface science and attracts tremendous interest in solving large‐scale practical problems. Recently, different super …
Membrane nanopores are key for molecular transport in biology, portable DNA sequencing,,– , label-free single-molecule analysis,,,,,,,,–and nanomedicine. Transport traditionally relies …
Y Feng, Y Zhang, C Ying, D Wang… - Genomics, Proteomics …, 2015 - academic.oup.com
Nanopore-based sequencers, as the fourth-generation DNA sequencing technology, have the potential to quickly and reliably sequence the entire human genome for less than 1000 …
S Howorka - Nature nanotechnology, 2017 - nature.com
Membrane nanopores—hollow nanoscale barrels that puncture biological or synthetic membranes—have become powerful tools in chemical-and biosensing, and have achieved …
There are still unmet needs in finding new technologies for biomedical diagnostic and industrial applications. A technology allowing the analysis of size and sequence of short …
Y Wu, JJ Gooding - Chemical Society Reviews, 2022 - pubs.rsc.org
Nanopore-based sensors typically work by monitoring transient pulses in conductance via current–time traces as molecules translocate through the nanopore. The unique property of …