The delivery of drugs through the oral route is regarded as most optimal to achieve desired
therapeutic effects and patient compliance. However, poor pharmacokinetic profiles of oral …

Background: Most of the active pharmaceutical ingredients discovered recently in
pharmaceutical field exhibits poor aqueous solubility that pose major problem in their oral …

Nanoemulsions have considerable potential for encapsulating, protecting and delivering
lipophilic bioactive components via the oral route, such as pharmaceuticals (drugs) and …

Objective Nintedanib (NDNB) is a triple receptor tyrosine kinase inhibitor with poor solubility
in neutral conditions and low bioavailability. A self-microemulsifying drug delivery system …

Despite its low water solubility, esculetin (EC) have been described to demonstrate various
health benefits. Thus, we sought to develop esculetin-loaded mixed micelles (EC-M) …

The objective of the current study was to explore the potential of nanostructured lipid carriers
(NLC) for oral delivery of docetaxel (DTX) and investigate the absorption mechanism in vivo …

Nanoemulsions (NE) are lipid nanocarriers that can efficiently load hydrophobic active
compounds, like palmitoyl-L-carnitine (pC), used here as model molecule. The use of design …

The specific chemotaxis of macrophages to inflammatory site makes them good candidate
for inflammation drug delivery. However, the loading capacity of free drug is low. The goal of …

Cerebral ischemia (CI) is associated with high global incidence and risk; therefore, its rapid
and reliable therapeutic management is essential for protecting patients' lives and improving …

Natural compounds are becoming popular for the treatment of illnesses and health
promotion, but the mechanisms of action and safety profiles are often unknown. Xyloketal B …