Excess adipose fat accumulation, or obesity, is a growing problem worldwide in terms of
both the rate of incidence and the severity of obesity-associated metabolic disease. Adipose …

A human organism depends on stable glucose blood levels in order to maintain its
metabolic needs. Glucose is considered to be the most important energy source, and …

High-sugar diets cause thirst, obesity, and metabolic dysregulation, leading to diseases
including type 2 diabetes and shortened lifespan. However, the impact of obesity and water …

Drosophila melanogaster has been widely used in the biological sciences as a model
organism. Drosophila has a relatively short life span of 60–80 days, which makes it attractive …

Although the Drosophila melanogaster (fly) model is a popular platform for investigating diet-
related phenomena, it can be challenging to measure the volume of agar-based food media …

Insulin‐like peptides (ILPs) belong to the insulin superfamily and act as hormones,
neuromediators, and growth factors during the post‐embryonic life‐cycle stages of insects …

Ageing is a major risk factor for many conditions including cancer, cardiovascular and
neurodegenerative diseases. Pharmaceutical interventions that slow down ageing and …

Fruit flies have eight identified Drosophila insulin-like peptides (DILPs) that are involved in
the regulation of carbohydrate concentrations in hemolymph as well as in accumulation of …

Overweight and obesity are health conditions tightly related to a number of metabolic
complications collectively called “metabolic syndrome”(MetS). Clinical diagnosis of MetS …

The deposition of storage fat in the form of triacylglycerol (TAG) is an evolutionarily
conserved strategy to cope with fluctuations in energy availability and metabolic stress …