Mammalian stress granules and P bodies at a glance

CL Riggs, N Kedersha, P Ivanov… - Journal of cell …, 2020 - journals.biologists.com
Stress granules (SGs) and processing bodies (PBs) are membraneless ribonucleoprotein-
based cellular compartments that assemble in response to stress. SGs and PBs form …

Stress granules and processing bodies in translational control

P Ivanov, N Kedersha… - Cold Spring Harbor …, 2019 - cshperspectives.cshlp.org
Stress granules (SGs) and processing bodies (PBs) are non-membrane-enclosed RNA
granules that dynamically sequester translationally inactive messenger ribonucleoprotein …

[HTML][HTML] G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits

N Kedersha, MD Panas, CA Achorn, S Lyons… - Journal of Cell …, 2016 - rupress.org
Mammalian stress granules (SGs) contain stalled translation preinitiation complexes that are
assembled into discrete granules by specific RNA-binding proteins such as G3BP. We now …

Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen

FJ Burt, W Chen, JJ Miner, DJ Lenschow… - The Lancet Infectious …, 2017 - thelancet.com
Re-emergence of chikungunya virus, a mosquito-transmitted pathogen, is of serious public
health concern. In the past 15 years, after decades of infrequent, sporadic outbreaks, the …

Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection

W Kamel, M Noerenberg, B Cerikan, H Chen… - Molecular cell, 2021 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). SARS-CoV-2 relies on cellular RNA-binding proteins (RBPs) to …

Mechanistic insights into mammalian stress granule dynamics

MD Panas, P Ivanov, P Anderson - Journal of Cell Biology, 2016 - rupress.org
The accumulation of stalled translation preinitiation complexes (PICs) mediates the
condensation of stress granules (SGs). Interactions between prion-related domains and …

Porcine epidemic diarrhea virus: An updated overview of virus epidemiology, virulence variation patterns and virus–host interactions

Y Zhang, Y Chen, J Zhou, X Wang, L Ma, J Li, L Yang… - Viruses, 2022 - mdpi.com
The porcine epidemic diarrhea virus (PEDV) is a member of the coronavirus family, causing
deadly watery diarrhea in newborn piglets. The global pandemic of PEDV, with significant …

SARS-CoV-2 nucleocapsid protein phase separates with G3BPs to disassemble stress granules and facilitate viral production

L Luo, Z Li, T Zhao, X Ju, P Ma, B Jin, Y Zhou, S He… - Science bulletin, 2021 - Elsevier
A key to tackling the coronavirus disease 2019 (COVID-19) pandemic is to understand how
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) manages to outsmart host …

Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage

J Jia, F Wang, Z Bhujabal, R Peters, M Mudd… - Journal of Cell …, 2022 - rupress.org
We report that lysosomal damage is a hitherto unknown inducer of stress granule (SG)
formation and that the process termed membrane atg8ylation coordinates SG formation with …

Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

T Kruse, C Benz, DH Garvanska, R Lindqvist… - Nature …, 2021 - nature.com
Viral proteins make extensive use of short peptide interaction motifs to hijack cellular host
factors. However, most current large-scale methods do not identify this important class of …