Since the emergence of regenerative medicine and tissue engineering more than half a
century ago, one obstacle has persisted: the in vitro creation of large-scale vascular tissue (> …

Abstract Three-dimensional (3D) bioprinting offers promising solutions to the complex
challenge of vascularization in biofabrication, thereby enhancing the prospects for clinical …

Abstract 3D multicellular aggregates, and more advanced organotypic systems, have
become central tools in recent years to study a wide variety of complex biological processes …

Coronary artery bypass grafting (CABG) remains the most common procedure used in
cardiovascular surgery for the treatment of severe coronary atherosclerotic heart disease. In …

Despite the efforts devoted to drug discovery and development, the number of new drug
approvals have been decreasing. Specifically, cardiovascular developments have been …

On‐demand drug delivery systems (DDSs) have tremendous promise for clinical in vivo
personalized drug delivery. However, the current DDSs are monofunctional and unable to …

Tissue-engineered vascular conduits (TEVCs), often made by seeding autologous bone
marrow cells onto biodegradable polymeric scaffolds, hold promise toward treating single …

In vitro models of the vasculature play an important role in biomedical discovery research,
with diverse applications in vascular biology, drug discovery, and tissue engineering. These …

Tissue engineered vascular grafts (TEVGs) represent a promising therapeutic option for
emergency vascular intervention. Although the application of small-diameter TEVGs using …

Fibrosis is a life-threatening pathological condition resulting from a dysfunctional tissue
repair process. There is no efficient treatment and organ transplantation is in many cases the …