Elucidating the Architectural dynamics of MuB filaments in bacteriophage Mu DNA transposition

X Zhao, Y Gao, Q Gong, K Zhang, S Li - Nature Communications, 2024 - nature.com
MuB is a non-specific DNA-binding protein and AAA+ ATPase that significantly influences
the DNA transposition process of bacteriophage Mu, especially in target DNA selection for …

Target DNA bending by the Mu transpososome promotes careful transposition and prevents its reversal

JR Fuller, PA Rice - Elife, 2017 - elifesciences.org
The transposition of bacteriophage Mu serves as a model system for understanding DDE
transposases and integrases. All available structures of these enzymes at the end of the …

Transposition Behavior Revealed by High-Resolution Description of Pseudomonas Aeruginosa Saltovirus Integration Sites

G Vergnaud, C Midoux, Y Blouin, M Bourkaltseva… - Viruses, 2018 - mdpi.com
Transposable phages, also called saltoviruses, of which the Escherichia coli phage Mu is
the reference, are temperate phages that multiply their genome through replicative …

The N-terminal domain of MuB protein has striking structural similarity to DNA-binding domains and mediates MuB filament–filament interactions

M Dramićanin, B López-Méndez, J Boskovic… - Journal of structural …, 2015 - Elsevier
MuB is an ATP-dependent DNA-binding protein that regulates the activity of MuA
transposase and delivers the target DNA for transposition of phage Mu. Mechanistic insight …