Update on treatments for endotoxemia

G Kelmer - Veterinary Clinics: Equine Practice, 2009 - vetequine.theclinics.com
Endotoxemia is a leading cause of morbidity, mortality, and economic loss to the equine
industry. 1 Colic, specifically intestinal strangulation, is the most common cause of …

Preservation of Platelets by Adding Epigallocatechin-3-O-Gallate to Platelet Concentrates

K Matsumura, H Takayama, JY Bae… - Cell …, 2009 - journals.sagepub.com
The effect of epigallocatechin-3-O-gallate (EGCG), a major component of green tea, on
platelet preservation was evaluated. Single donor platelets (N= 10) were collected and …

Breast cancer cell-induced platelet activation is compounded by tamoxifen and anastrozole in vitro

K Pather, T Dix-Peek, R Duarte, N Chetty… - Thrombosis …, 2019 - Elsevier
Platelet-tumour cell interaction is implicated in the initiation of breast cancer-associated
thrombosis, with hormone-therapy (Tamoxifen/Anastrozole), increasing this risk. However …

Evaluation of dimethyl sulphoxide effects on initial response to endotoxin in the horse

G Kelmer, TJ Doherty, S Elliott, A Saxton… - Equine veterinary …, 2008 - Wiley Online Library
Reasons for performing study: Endotoxaemia is one of the most severe and ubiquitous
disease processes in horses. Although dimethyl sulphoxide (DMSO) is used clinically in …

Prolonged platelet preservation by transient metabolic suppression

BA Badlou, MJW Ijseldijk, WM Smid… - Transfusion, 2005 - Wiley Online Library
BACKGROUND: In this study whether metabolic suppression can be used to preserve
platelet (PLT) function during prolonged storage was investigated. STUDY DESIGN AND …

Low concentration detergent sclerosants induce platelet activation but inhibit aggregation due to suppression of GPIIb/IIIa activation in vitro

K Parsi, DE Connor, A Pilotelle, J Low, DDF Ma… - Thrombosis research, 2012 - Elsevier
INTRODUCTION: Sclerotherapy is associated with thromboembolic and ischemic
neurological adverse events but the effects of sclerosants on platelet function are unknown …

Analysis of a commercial dimethyl‐sulfoxide‐stabilized frozen canine platelet concentrate by turbidimetric aggregometry

J Guillaumin, KE Jandrey, JW Norris… - Journal of Veterinary …, 2010 - Wiley Online Library
Objectives–To assess platelet function of a commercial dimethyl‐sulfoxide (DMSO)‐
stabilized frozen platelet concentrate (PC) using turbidimetric aggregometry. Design–In vitro …

The treatment of diarrhoea in the adult horse

RJ Naylor, B Dunkel - Equine veterinary education, 2009 - Wiley Online Library
The priority in treating the equine patient with acute diarrhoea is to stabilise the
haemodynamic aberrations secondary to the fluid and electrolyte losses. Once this has been …

Metabolic energy reduction by glucose deprivation and low gas exchange preserves platelet function after 48 h storage at 4 C

BA Badlou, PF Van Der Meer, JWN Akkerman… - Vox …, 2007 - Wiley Online Library
Introduction We showed earlier that metabolically suppressed platelets (MSP) prepared by
incubation in glucose‐free, antimycin A medium at 37° C better sustained storage at 4° C …

Effect of nitric oxide on the cryopreservation of platelets

JH Lee, JT Kim, YG Cho - The Korean Journal of Laboratory …, 2008 - synapse.koreamed.org
Background To determine whether nitric oxide (NO) could inhibit activation of platelets
stored in a cold or frozen state, we measured platelet P-selectin expression and platelet …