Diabetes mellitus (DM) appears to be increasing rapidly, threatening to reduce life
expectancy for humans around the globe. The International Diabetes Federation (IDF) has …

Insulin resistance (IR) is a pathological condition strongly associated with obesity. However,
corticosteroids or growth hormone therapy and genetic diseases may affect insulin …

Background Metabolic syndrome over the years have structured definitions to classify an
individual with the disease. Literature review suggests insulin résistance is hallmark of these …

Aims Insulin resistance (IR) may develop very early in life being associated with occurrence
of cardiometabolic risk factors (CMRFs). Aim of the present study was to identify in young …

Context: The concept of metabolic healthy obese (MHO) status has been proposed also for
children. However, it is unclear whether this is a stable status in childhood. Objective: The …

METHODS: The Teen-Longitudinal Assessment of Bariatric Surgery study (NCT00474318)
prospectively collected anthropometric and health status data on 242 adolescents …

(1) Background: Overt and subclinical hypothyroidism has been associated with increased
cardiometabolic risks. Here we further explore whether thyroid function within normal range …

Pediatricians increasingly diagnose the metabolic syndrome (MetS) in recent years to
describe cardiovascular risk and to guide management of the obese child. However, there is …

Objective. To determine the optimal cutoff of the homeostasis model assessment‐insulin
resistance (HOMA‐IR) for diagnosis of the metabolic syndrome (MetS) in adolescents and …

Context: Available data related to the metabolically healthy obesity (MHO) phenotype are
mainly derived from studies in adults because studies during childhood are very limited to …