The development of therapeutic cancer vaccines as a means to generate immune reactivity
against tumors has been explored since the early discovery of tumor-specific antigens by …

Synthetic polypeptides are biocompatible and biodegradable macromolecules whose
composition and architecture can vary over a wide range. Their unique ability to form …

Protein-mimetic amphiphiles have significant promise as a platform to access the complex
functions of natural biological materials and incorporate the tunability and environmental …

The utility of layer-by-layer (LbL) coated microneedle (MN) skin patches for transdermal drug
delivery has proven to be a promising approach, with advantages over hypodermal injection …

Silk sericin (SS) is a natural water-soluble protein with the potential to chelate metal ions via
its polar groups. However, the difficulty of identifying the saturation of SS limits its application …

Vaccines are one of the best health care advances ever developed, having led to the
eradication of smallpox and near eradication of polio and diphtheria. While tremendously …

Peptide amphiphile micelles (PAMs) are attractive vehicles for the delivery of a variety of
therapeutic and prophylactic peptides. However, a key limitation of PAMs is their lack of …

Current vaccine research has shifted from traditional vaccines (ie, whole-killed or live-
attenuated) to subunit vaccines (ie, protein, peptide, or DNA) as the latter is much safer due …

Two different vasoactive intestinal peptide (VIP) amphiphiles have been formulated which
readily form micelles of varying shapes. Interestingly, VIP micelle structure has been found …

Traditional vaccines such as live-attenuated or whole-killed vaccines have been widely
used over the past hundred years. However, the safety and effectiveness of traditional …