miR‐155: an ancient regulator of the immune system

E Vigorito, S Kohlhaas, D Lu… - Immunological reviews, 2013 - Wiley Online Library
Micro RNA s (mi RNA s) are a newly recognized class of regulatory genes which repress the
expression of protein‐coding genes. Numerous studies have uncovered a complex role for …

The Myc oncoprotein as a therapeutic target for human cancer

M Vita, M Henriksson - Seminars in cancer biology, 2006 - Elsevier
Myc expression is deregulated in a wide range of human cancers and is often associated
with aggressive, poorly differentiated tumors. The Myc protein is a transcription factor that …

miR-122 targeting with LNA/2′-O-methyl oligonucleotide mixmers, peptide nucleic acids (PNA), and PNA–peptide conjugates

MM Fabani, MJ Gait - Rna, 2008 - rnajournal.cshlp.org
MicroRNAs are small noncoding RNAs that regulate many cellular processes in a post-
transcriptional mode. MicroRNA knockdown by antisense oligonucleotides is a useful …

Chemical approaches to discover the full potential of peptide nucleic acids in biomedical applications

N Brodyagin, M Katkevics, V Kotikam… - Beilstein journal of …, 2021 - beilstein-journals.org
Peptide nucleic acid (PNA) is arguably one of the most successful DNA mimics, despite a
most dramatic departure from the native structure of DNA. The present review summarizes …

Efficient inhibition of miR-155 function in vivo by peptide nucleic acids

MM Fabani, C Abreu-Goodger, D Williams… - Nucleic acids …, 2010 - academic.oup.com
MicroRNAs (miRNAs) play an important role in diverse physiological processes and are
potential therapeutic agents. Synthetic oligonucleotides (ONs) of different chemistries have …

Cell penetrating peptide conjugates of steric block oligonucleotides

B Lebleu, HM Moulton, R Abes, GD Ivanova… - Advanced drug delivery …, 2008 - Elsevier
Charge neutral steric block oligonucleotide analogues, such as peptide nucleic acids (PNA)
or phosphorodiamidate morpholino oligomers (PMO), have promising biological and …

[图书][B] Handbook of cell-penetrating peptides

U Langel - 2006 - taylorfrancis.com
Since the first Handbook of Cell-Penetrating Peptides was prepared in 2001, the wealth of
new information on the use of these peptides as transport systems has in fact served to …

[HTML][HTML] Potential of peptide nucleic acids in future therapeutic applications

S Montazersaheb, MS Hejazi… - Advanced …, 2018 - ncbi.nlm.nih.gov
Peptide nucleic acids (PNA) are synthetic analog of DNA with a repeating N-(2-aminoethyl)-
glycine peptide backbone connected to purine and pyrimidine nucleobases via a linker …

[HTML][HTML] Voltage-dependant anion channels: novel insights into isoform function through genetic models

A Raghavan, T Sheiko, BH Graham… - Biochimica et Biophysica …, 2012 - Elsevier
Voltage-dependant Anion Channels, also known as mitochondrial porins, are pore-forming
proteins located in the mitochondrial outer membrane (MOM) that, in addition to forming …

Biology and treatment of Burkitt's lymphoma

JT Yustein, CV Dang - Current opinion in hematology, 2007 - journals.lww.com
Burkitt's lymphoma is an interesting mature B-cell non-Hodgkin's lymphoma that has
numerous distinct features and clinical variants depending on factors such as geographical …