Impact of aging on the pathophysiology of dry eye disease: A systematic review and meta-analysis

K Kitazawa, T Inomata, K Shih, JWB Hughes, N Bozza… - The Ocular Surface, 2022 - Elsevier
Purpose Dry eye disease (DED) is a common age-related ocular surface disease. However,
it is unknown how aging influences the ocular surface microenvironment. This systematic …

Blepharitis preferred practice pattern®

G Amescua, EK Akpek, M Farid, FJ Garcia-Ferrer… - …, 2019 - aaojournal.org
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The global prevalence of dry eye disease: A Bayesian view

EB Papas - Ophthalmic and Physiological optics, 2021 - Wiley Online Library
Purpose To provide estimates for the prevalence of dry eye disease globally and in sub‐
groups defined by: diagnostic criterion, sex, geographic location and age, using a Bayesian …

Meibomian gland stem/progenitor cells: the hunt for gland renewal

X Yang, LW Reneker, X Zhong, AJW Huang… - The Ocular Surface, 2023 - Elsevier
Meibomian glands (MGs) secrete lipid (meibum) onto the ocular surface to form the
outermost layer of the tear film. Proper meibum secretion is essential for stabilizing the tear …

Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and …

S An, I Raju, B Surenkhuu, JE Kwon, S Gulati… - The ocular …, 2019 - Elsevier
Purpose To investigate the role of neutrophil extracellular traps (NETs) and NET-associated
proteins in the pathogenesis of oGVHD and whether dismantling of NETs with heparin …

DEBS–a unification theory for dry eye and blepharitis

JM Rynerson, HD Perry - Clinical Ophthalmology, 2016 - Taylor & Francis
For many years, blepharitis and dry eye disease have been thought to be two distinct
diseases, and evaporative dry eye distinct from aqueous insufficiency. In this treatise, we …

Prevalence of meibomian gland atrophy in a pediatric population

PK Gupta, MN Stevens, N Kashyap, Y Priestley - Cornea, 2018 - journals.lww.com
Purpose: To report the prevalence of meibomian gland atrophy and gland tortuosity in a
pediatric population. Methods: Participants who presented with no history of dry eye disease …

Meibomian gland dysfunction: what have animal models taught us?

M Sun, IY Moreno, M Dang… - International Journal of …, 2020 - mdpi.com
Studies have estimated that currently 344 million people worldwide and 16.4 million adults
in the US have some form of dry eye disease (DED). It is believed that approximately 70% of …

[HTML][HTML] New insights into the morphology and function of meibomian glands

R Arita, S Fukuoka, N Morishige - Experimental eye research, 2017 - Elsevier
Meibomian glands secrete meibum, which gives rise to the lipid layer of the tear film and
thereby prevents excessive evaporation of tear fluid. Meibomian gland dysfunction (MGD) is …

Recent advances in age-related meibomian gland dysfunction (ARMGD)

I Moreno, S Verma, TF Gesteira, VJ Coulson-Thomas - The Ocular Surface, 2023 - Elsevier
Meibomian glands (MGs), located within the tarsal plate of the eyelid, secrete meibum which
is the lipid-rich secretion necessary for stabilizing the tear film and preventing tear …