Mechanisms of Neurotoxicity of Organophosphate Pesticides and Their Relation to Neurological Disorders

Y Chen, Z Yang, B Nian, C Yu, D Maimaiti… - Neuropsychiatric …, 2024 - Taylor & Francis
Organophosphates (OPs) refers to a diverse group of phosphorus-containing organic
compounds; they are widely used all over the world and have had an important beneficial …

Comprehensive investigation of the mutagenic potential of six pesticides classified by IARC as probably carcinogenic to humans

R Martinek, R Lózsa, Á Póti, E Németh, G Várady… - Chemosphere, 2024 - Elsevier
Pesticides are significant environmental pollutants, and many of them possess mutagenic
potential, which is closely linked to carcinogenesis. Here we tested the mutagenicity of all six …

Ameliorative effect of thymoquinone and thymoquinone nanoparticles against diazinon-induced hepatic injury in rats: A possible protection mechanism

WM Nassar, WM El-Kholy, MR El-Sawi, NM El-Shafai… - Toxics, 2023 - mdpi.com
The health benefits of thymoquinone (TQ) have been a significant focus of numerous
studies. However, more research is needed to ascertain whether its nano-form can …

Mycodegradation of diazinon pesticide utilizing fungal strains isolated from polluted soil

AAF Mostafa, MT Yassin, TM Dawoud, FO Al-Otibi… - Environmental …, 2022 - Elsevier
The current study aimed to isolate biodegradable soil fungi capable of metabolizing
diazinon. The collected soil samples were investigated for diazinon pollution to detect the …

Potential protective effects of chrysin against immunotoxicity induced by diazinon

M Zeinali, A Shafaei, H Rafatpanah, A Mosavat… - Scientific Reports, 2022 - nature.com
Acute intoxication with diazinon (DZN) as a pesticide causes mortality and morbidity
annually. This study shows the impact of sub-acute toxicity of DZN 20 mg/kg and the …

[HTML][HTML] Role of biotransformation in the diazinon-induced toxicity in HepG2 cells and antioxidant protection by tetrahydrocurcumin

CA Miranda, EM Beretta, LA Ferreira, ES da Silva… - Toxicology Reports, 2023 - Elsevier
Diazinon (DZN) is an insecticide extensively used to control pests in crops and animals.
However, its indicriminated use may lead to liver damage in animals and humans. This …

Effects of diazinon on the ovarian tissue of rats: a histochemical and ultrastructural study

F Abou Hasan, HS Mutlu, İ Özdemir, T Kotil - Journal of Molecular …, 2024 - Springer
Despite the negative environmental and biologic effects, organophosphates have currently
been widely used. We aimed to examine the possible negative effects of diazinon, a type of …

A photoelectrochemical aptasensor based on W6+-doped carbon nitride with carbon-rich structure for sensitive detection of diazinon

R Zhi, Y Chen, P Yan, M Ling, S Dong, L Xu, H Li - Microchimica Acta, 2024 - Springer
A photoelectrochemical (PEC) aptasensor us reported based on W6+-doped carbon nitride
with carbon-rich structure (WCCN). WCCN exhibited excellent photoelectric conversion …

Malignant growth of arsenic-transformed cells depends on activated Akt induced by reactive oxygen species

Q Lou, F Chen, B Li, M Zhang, F Yin, X Liu… - International Journal …, 2023 - Taylor & Francis
Arsenic is an identified carcinogen for humans. In this study, chronic exposure of human
hepatocyte L-02 to low-doses of inorganic arsenic caused cell malignant proliferation …

The protective effect of methanolic extract of Verbascum cheiranthifolium and Biebersteinia multifida DC on hippocampus damage induced by diazinon in male Wistar …

A Delavar, FR Anbarkeh, R Baradaran, Z Arab… - Journal of Chemical …, 2024 - Elsevier
Diazinon (DZN) an organophosphate (OP), with the most important mechanism of action of
DZN being induction of oxidative stress (OS) and inhibition of the enzyme …