Spinal cord injury remains a scientific and therapeutic challenge with great cost to
individuals and society. The goal of research in this field is to find a means of restoring lost …

Epidermal growth factor receptor (EGFR) is the first discovered member of the receptor
tyrosine kinase superfamily and plays a fundamental role during embryogenesis and in …

Sphere-forming assays have been widely used to retrospectively identify stem cells based
on their reported capacity to evaluate self-renewal and differentiation at the single-cell level …

Neural stem cells reside in the subventricular zone (SVZ) of the adult mammalian brain. This
germinal region, which continually generates new neurons destined for the olfactory bulb, is …

Spinal cord injury (SCI) leads to irreversible neuronal loss and glial scar formation, which
ultimately result in persistent neurological dysfunction. Cellular regeneration could be an …

Spinal cord injuries (SCIs) are associated with tremendous physical, social, and financial
costs for millions of individuals and families worldwide. Rapid delivery of specialized …

Oligodendrocytes, the myelin-forming cells of the central nervous system (CNS), and
astrocytes constitute macroglia. This review deals with the recent progress related to the …

The highly disagreeable sensation of pain results from an extraordinarily complex and
interactive series of mechanisms integrated at all levels of the neuroaxis, from the periphery …

The adult mammalian subventricular zone (SVZ) contains stem cells that give rise to
neurons and glia. In vivo, SVZ progeny migrate 3–8 mm to the olfactory bulb, where they …

Several distinct cell types in the adult central nervous system have been suggested to act as
stem or progenitor cells generating new cells under physiological or pathological conditions …