Magnetic resonance elastography from fundamental soft-tissue mechanics to diagnostic imaging

I Sack - Nature Reviews Physics, 2023 - nature.com
Magnetic resonance elastography (MRE) is a versatile imaging technique for mapping the
viscoelastic properties of soft biological tissues. It has been widely used to detect liver …

MR elastography in cancer

J Guo, LJ Savic, KH Hillebrandt, I Sack - Investigative Radiology, 2023 - journals.lww.com
The mechanical traits of cancer include abnormally high solid stress as well as drastic and
spatially heterogeneous changes in intrinsic mechanical tissue properties. Whereas solid …

Changes in tissue fluidity predict tumor aggressiveness in vivo

F Sauer, S Grosser, M Shahryari, A Hayn… - Advanced …, 2023 - Wiley Online Library
Cancer progression is caused by genetic changes and associated with various alterations in
cell properties, which also affect a tumor's mechanical state. While an increased stiffness …

Mechanical properties of murine hippocampal subregions investigated by atomic force microscopy and in vivo magnetic resonance elastography

AS Morr, M Nowicki, G Bertalan, R Vieira Silva… - Scientific Reports, 2022 - nature.com
The hippocampus is a very heterogeneous brain structure with different mechanical
properties reflecting its functional variety. In particular, adult neurogenesis in rodent …

Rigid tumours contain soft cancer cells

T Fuhs, F Wetzel, AW Fritsch, X Li, R Stange… - Nature Physics, 2022 - nature.com
Palpation utilizes the fact that solid breast tumours are stiffer than the surrounding tissue.
However, cancer cells tend to soften, which may enhance their ability to squeeze through …

Mask region-based CNNs for cervical cancer progression diagnosis on pap smear examinations

CR de Lima, SG Khan, SH Shah, L Ferri - Heliyon, 2023 - cell.com
This research presents a novel approach for cervical cancer detection and segmentation
using tissue images with multiple cells. The study employs a novel deep learning …

Effect of non-linear strain stiffening in eDAH and unjamming

X Xie, F Sauer, S Grosser, J Lippoldt, E Warmt, A Das… - Soft Matter, 2024 - pubs.rsc.org
In cell clusters, the prominent factors at play encompass contractility-based enhanced tissue
surface tension and cell unjamming transition. The former effect pertains to the boundary …

Literature review: potential non-thermal molecular effects of external radiofrequency electromagnetic fields on cancer

A Dieper, S Scheidegger, RM Füchslin… - International Journal …, 2024 - Taylor & Francis
Introduction There is an ongoing scientific discussion, that anti-cancer effects induced by
radiofrequency (RF)-hyperthermia might not be solely attributable to subsequent …

[HTML][HTML] Magnetic resonance elastography in a nutshell: Tomographic imaging of soft tissue viscoelasticity for detecting and staging disease with a focus on …

T Meyer, J Castelein, J Schattenfroh, AS Morr… - Progress in Nuclear …, 2024 - Elsevier
Magnetic resonance elastography (MRE) is an emerging clinical imaging modality for
characterizing the viscoelastic properties of soft biological tissues. MRE shows great …

The networking brain: how extracellular matrix, cellular networks, and vasculature shape the in vivo mechanical properties of the brain

J Bergs, AS Morr, RV Silva, C Infante‐Duarte… - Advanced …, 2024 - Wiley Online Library
Mechanically, the brain is characterized by both solid and fluid properties. The resulting
unique material behavior fosters proliferation, differentiation, and repair of cellular and …