Humans are infected by four recognized species of malaria parasites. The last of these to be
recognized and described is Plasmodium ovale. Like the other malaria parasites of …

Malaria is a vector-borne infection caused by unicellular parasite of the genus Plasmodium.
Plasmodia are obligate intracellular parasites that are able to infect and replicate within the …

Experimental studies of Plasmodium parasites that infect humans are restricted by their host
specificity. Humanized mice offer a means to overcome this and further provide the …

Plasmodium undergoes one round of multiplication in the liver prior to invading erythrocytes
and initiating the symptomatic blood phase of the malaria infection. Productive hepatocyte …

Plasmodium ovale was the last of the exclusively human malaria parasites to be described,
in 1922, and has remained the least well studied. Beginning in 1995, two divergent forms of …

Background Despite increased efforts to control and ultimately eradicate human malaria,
Plasmodium ovale malaria is for the most part outside the focus of research or public health …

Previous work in this laboratory has demonstrated the ability of the immunofluorescence
technique to detect pre-erythrocytic stages of the primate malaria parasite, Plasmodium …

Erythrocytes are formed from the enucleation of erythroblasts in the bone marrow, and as
erythrocytes develop from immature reticulocytes into mature normocytes, they undergo …

Relapsing human malaria is regarded to be caused by Plasmodium vivax and Plasmodium
ovale. P. vivax relapses originate from dormant liver stages:“hypnozoites”. Also, P. ovale, a …

Background Malaria remains a major public health concern in the Democratic Republic of
Congo (DRC), and school-age children are relatively neglected in malaria prevalence …