mRNA stability in mammalian cells
J Ross - Microbiological reviews, 1995 - Am Soc Microbiol
This review concerns how cytoplasmic mRNA half-lives are regulated and how mRNA decay
rates influence gene expression. mRNA stability influences gene expression in virtually all …
rates influence gene expression. mRNA stability influences gene expression in virtually all …
Transcriptional control of osteoblast growth and differentiation
GS Stein, JB Lian, JL Stein… - Physiological …, 1996 - journals.physiology.org
Osteoblast differentiation is a multistep series of events modulated by an integrated cascade
of gene expression that initially supports proliferation and the sequential expression of …
of gene expression that initially supports proliferation and the sequential expression of …
Identification of genes periodically expressed in the human cell cycle and their expression in tumors
ML Whitfield, G Sherlock, AJ Saldanha… - Molecular biology of …, 2002 - Am Soc Cell Biol
The genome-wide program of gene expression during the cell division cycle in a human
cancer cell line (HeLa) was characterized using cDNA microarrays. Transcripts of> 850 …
cancer cell line (HeLa) was characterized using cDNA microarrays. Transcripts of> 850 …
The poly (A)-poly (A)-binding protein complex is a major determinant of mRNA stability in vitro
P Bernstein, SW Peltz, J Ross - Molecular and cellular biology, 1989 - Taylor & Francis
Using an in vitro mRNA decay system, we investigated how poly (A) and its associated poly
(A)-binding protein (PABP) affect mRNA stability. Cell extracts used in the decay reactions …
(A)-binding protein (PABP) affect mRNA stability. Cell extracts used in the decay reactions …
Quantitative mRNA expression analysis from formalin-fixed, paraffin-embedded tissues using 5′ nuclease quantitative reverse transcription-polymerase chain …
TE Godfrey, SH Kim, M Chavira, DW Ruff… - The Journal of molecular …, 2000 - Elsevier
Analysis of gene expression and correlation with clinical parameters has the potential to
become an important factor in therapeutic decision making. The ability to analyze gene …
become an important factor in therapeutic decision making. The ability to analyze gene …
Control of messenger RNA stability in higher eukaryotes
J Ross - Trends in Genetics, 1996 - cell.com
The mRNA decay rate (half-life) is a major determimmt of mPJlh abutufa~ e tn orgaBisms
from bacterta to mlO~ A lwet. s cam t'luaMU many~ ald fdtowing a clm~ e tl mRNA half 41fe …
from bacterta to mlO~ A lwet. s cam t'luaMU many~ ald fdtowing a clm~ e tl mRNA half 41fe …
Stem-loop binding protein, the protein that binds the 3′ end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanisms
ML Whitfield, LX Zheng, A Baldwin, T Ohta… - … and cellular biology, 2000 - Am Soc Microbiol
The expression of the replication-dependent histone mRNAs is tightly regulated during the
cell cycle. As cells progress from G 1 to S phase, histone mRNA levels increase 35-fold, and …
cell cycle. As cells progress from G 1 to S phase, histone mRNA levels increase 35-fold, and …
Do the poly (A) tail and 3′ untranslated region control mRNA translation?
RJ Jackson, N Standart - Cell, 1990 - Elsevier
From the date of its discovery in 1970, the 3'poly (A) tail of eukaryotic mRNA has taken on
the character of a structure in search of a function. Candidate functions favored in those far …
the character of a structure in search of a function. Candidate functions favored in those far …
Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant.
PL Bernstein, DJ Herrick, RD Prokipcak… - Genes & …, 1992 - genesdev.cshlp.org
Polysome-associated c-myc mRNA is degraded relatively rapidly in cells and in an in vitro
mRNA decay system containing extracts from cultured mammalian cells. Using this system …
mRNA decay system containing extracts from cultured mammalian cells. Using this system …
Ectopic expression of AINTEGUMENTA in Arabidopsis plants results in increased growth of floral organs
BA Krizek - Developmental genetics, 1999 - Wiley Online Library
AINTEGUMENTA (ANT) was previously shown to be involved in floral organ initiation and
growth in Arabidopsis. ant flowers have fewer and smaller floral organs and possess ovules …
growth in Arabidopsis. ant flowers have fewer and smaller floral organs and possess ovules …