The common and persistent failures to translate promising preclinical drug candidates into
clinical success highlight the limited effectiveness of disease models currently used in drug …

The model of biofilm infection was first proposed over a decade ago. Recent scientific
advances have added much to our understanding of biofilms, usually polymicrobial …

There is increasing evidence that bacterial biofilm is responsible for the failure of medical
devices, leading to device-associated infection. As plastic surgeons, we are among the …

A central challenge in microbial community ecology is the delineation of appropriate units of
biodiversity, which can be taxonomic, phylogenetic, or functional in nature. The term …

The demand for joint replacement surgery is continuously increasing with rising costs for
hospitals and healthcare systems. Staphylococci are the most prevalent etiological agents of …

Aims: The focus of this study was to evaluate the potential use of the predatory bacteria
Bdellovibrio bacteriovorus and Micavibrio aeruginosavorus to control the pathogens …

Gardnerella vaginalis is associated with a spectrum of clinical conditions, suggesting high
degrees of genetic heterogeneity among stains. Seventeen G. vaginalis isolates were …

Sequencing DNA from single cells has opened new windows onto the microbial world. It is
becoming routine to sequence bacterial species directly from environmental samples or …

If discovery of new antibiotics continues to falter while resistance to drugs in clinical use
continues to spread, society's medicine chest will soon lack effective treatments for many …

Background Over the last few decades, a growing body of evidence suggests a role for
various infectious agents in Alzheimer's Disease (AD) pathogenesis. Despite diverse …