Altered synaptic connectivity and brain function in mice lacking microglial adapter protein Iba1

PJ Lituma, E Woo, BF O'Hara… - Proceedings of the …, 2021 - National Acad Sciences
Growing evidence indicates that microglia impact brain function by regulating synaptic
pruning and formation as well as synaptic transmission and plasticity. Iba1 (ionized Ca+ 2 …

Early or late gestational exposure to maternal immune activation alters neurodevelopmental trajectories in mice: an integrated neuroimaging, behavioral, and …

E Guma, P do Couto Bordignon, GA Devenyi… - Biological …, 2021 - Elsevier
Background Exposure to maternal immune activation (MIA) in utero is a risk factor for
neurodevelopmental disorders later in life. The impact of the gestational timing of MIA …

The membrane-linked adaptor FRS2β fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis

Y Takeuchi, N Kimura, T Murayama… - Proceedings of the …, 2021 - National Acad Sciences
Although it is held that proinflammatory changes precede the onset of breast cancer, the
underlying mechanisms remain obscure. Here, we demonstrate that FRS2β, an adaptor …

The Interaction of EphA4 With PDGFRβ Regulates Proliferation and Neuronal Differentiation of Neural Progenitor Cells in vitro and Promotes Neurogenesis in vivo

Q Chen, H Song, C Liu, J Xu, C Wei… - Frontiers in Aging …, 2020 - frontiersin.org
Neural progenitor cells (NPCs) have great potentials in cell replacement therapy for
neurodegenerative diseases, such as Alzheimer's disease (AD), by promoting neurogenesis …

Transcriptional activity of neurotrophins genes and their receptors in the peripheral blood in patients with thyroid diseases in Bukovinian population of Ukraine

I Kamyshna, A Kamyshnyi - Open Access Macedonian Journal of …, 2021 - oamjms.eu
AIM: Thyroid hormone (TH) has an especially strong impact on central nervous system
development and TH deficiency has been shown to result in severe mental retardation. It is …

Proteome Analysis of the Hypothalamic Arcuate Nucleus in Chronic High‐Fat Diet‐Induced Obesity

CY Kim, JH Ahn, DH Han… - BioMed Research …, 2021 - Wiley Online Library
The hypothalamus plays a central role in the integrated regulation of feeding and energy
homeostasis. The hypothalamic arcuate nucleus (ARC) contains a population of neurons …

FGFR regulation of dendrite elaboration in adult-born granule cells depends on intracellular mediator and proximity to the soma

M Grońska-Pęski, W Mowrey, JM Hébert - Neuroscience, 2021 - Elsevier
Abstract Fibroblast Growth Factor Receptors (FGFRs) play crucial roles in promoting
dendrite growth and branching during development. In mice, three FGFR genes, Fgfr1 …

Молекулярні механізми розвитку психоневрологічних ускладнень у пацієнтів з захворюваннями щитоподібної залози: прогнозування виникнення і пошук …

ІІ Камишна - 2023 - repository.tdmu.edu.ua
Дисертація присвячена клінічно-патогенетичним особливостям психоневрологічних
порушень за патології щитоподібної залози (ЩЗ), ключовим молекулярним механізмам …

[图书][B] Mechanisms of Information Transfer and Storage in the Mammalian Hippocampus

PJ Lituma - 2021 - search.proquest.com
Sensory experience elicits neural activity that triggers cellular and molecular processes to
support the transfer and storage of environmental information in the central nervous system …

[PDF][PDF] Neurobehavioral consequences of perinatal high-fat diet exposure: Toward understanding and intervention

SG Khambadkone - 2020 - jscholarship.library.jhu.edu
It is clear that an adverse perinatal environment can prime risk for neuropsychiatric disease.
Maternal obesity and globalization of the Western-style diet is a public health concern and …