Advanced MR techniques for preoperative glioma characterization: Part 1

L Hirschler, N Sollmann… - Journal of Magnetic …, 2023 - Wiley Online Library
Preoperative clinical magnetic resonance imaging (MRI) protocols for gliomas, brain tumors
with dismal outcomes due to their infiltrative properties, still rely on conventional structural …

Non-invasive evaluation of cerebral microvasculature using pre-clinical MRI: principles, advantages and limitations

B Callewaert, EAV Jones, U Himmelreich, W Gsell - Diagnostics, 2021 - mdpi.com
Alterations to the cerebral microcirculation have been recognized to play a crucial role in the
development of neurodegenerative disorders. However, the exact role of the microvascular …

Imaging vascular and hemodynamic features of the brain using dynamic susceptibility contrast and dynamic contrast enhanced MRI

CC Quarles, LC Bell, AM Stokes - Neuroimage, 2019 - Elsevier
In the context of neurologic disorders, dynamic susceptibility contrast (DSC) and dynamic
contrast enhanced (DCE) MRI provide valuable insights into cerebral vascular function …

Concurrent measurement of perfusion parameters related to small blood vessels and cerebrospinal fluid circulation in the human brain using dynamic dual‐spin‐echo …

D Cao, Y Sun, Y Li, P Su, JJ Pillai, Y Qiao… - NMR in …, 2023 - Wiley Online Library
Accumulating evidence from recent studies has indicated the importance of studying the
interaction between the microvascular and lymphatic systems in the brain. To date, most …

[HTML][HTML] A population-based digital reference object (DRO) for optimizing dynamic susceptibility contrast (DSC)-MRI methods for clinical trials

NB Semmineh, AM Stokes, LC Bell… - …, 2017 - pmc.ncbi.nlm.nih.gov
The standardization and broad-scale integration of dynamic susceptibility contrast (DSC)-
magnetic resonance imaging (MRI) have been confounded by a lack of consensus on DSC …

Aberrant vascular architecture in the hippocampus correlates with tau burden in mild cognitive impairment and Alzheimer's disease

H Lee, JF Fu, K Gaudet, AG Bryant… - Journal of Cerebral …, 2024 - journals.sagepub.com
Cerebrovascular dysfunction is a significant contributor to Alzheimer's disease (AD)
progression. AD mouse models show altered capillary morphology, density, and diminished …

Chronic cognitive and cerebrovascular function after mild traumatic brain injury in rats

DR Griffiths, LM Law, C Young, A Fuentes… - Journal of …, 2022 - liebertpub.com
Severe traumatic brain injury (TBI) results in cognitive dysfunction in part due to vascular
perturbations. In contrast, the long-term vasculo-cognitive pathophysiology of mild TBI …

Optimization and validation of multi-echo, multi-contrast SAGE acquisition in fMRI

EG Keeling, M Bergamino, S Ragunathan… - Imaging …, 2024 - direct.mit.edu
The purpose of this study was to optimize and validate a multi-contrast, multi-echo fMRI
method using a combined spin-and gradient-echo (SAGE) acquisition. It was hypothesized …

A simplified spin and gradient echo approach for brain tumor perfusion imaging

AM Stokes, CC Quarles - Magnetic resonance in medicine, 2016 - Wiley Online Library
Purpose In this study, we propose a simplified acquisition and analysis approach for spin
and gradient echo (SAGE)‐based dynamic susceptibility‐contrast MRI (DSC‐MRI) data that …

Development of a spiral spin‐and gradient‐echo (spiral‐SAGE) approach for improved multi‐parametric dynamic contrast neuroimaging

AM Stokes, S Ragunathan, RK Robison… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose The purpose of this study was to develop a spiral‐based combined spin‐and
gradient‐echo (spiral‐SAGE) method for simultaneous dynamic contrast‐enhanced (DCE …