Radiation therapy for uveal melanoma: a review of treatment methods available in 2021

DA Reichstein, AL Brock - Current opinion in ophthalmology, 2021 - journals.lww.com
Each particular radiotherapy technique employed to treat uveal melanoma has its own set of
benefits and drawbacks. The ocular oncologist can choose amongst these therapies based …

Radioactive iodine-125 in tumor therapy: advances and future directions

S Wei, C Li, M Li, Y Xiong, Y Jiang, H Sun, B Qiu… - Frontiers in …, 2021 - frontiersin.org
Radioactive iodine-125 (I-125) is the most widely used radioactive sealed source for
interstitial permanent brachytherapy (BT). BT has the exceptional ability to deliver extremely …

Long-term relative survival in uveal melanoma: a systematic review and meta-analysis

G Stålhammar, C Herrspiegel - Communications Medicine, 2022 - nature.com
Background A large proportion of patients with uveal melanoma develop metastases and
succumb to their disease. Reports on the size of this proportion vary considerably. Methods …

Forty-year prognosis after plaque brachytherapy of uveal melanoma

G Stålhammar - Scientific Reports, 2020 - nature.com
In this study, the long-term patient survival after plaque brachytherapy of uveal melanoma is
examined. All patients treated between 1980 and 1999 at a single institution were included …

Radiation retinopathy: detection and management strategies

NK Sahoo, R Ranjan, M Tyagi, H Agrawal… - Clinical …, 2021 - Taylor & Francis
A gradual shift in trend from primary enucleation to globe salvaging radiation therapy for the
management of ocular tumors has resulted in the rise of several post-treatment ocular …

Recent approaches for the treatment of uveal melanoma: Opportunities and challenges

SA Khan, WH Almalki, SJ Arora… - Critical Reviews in …, 2023 - Elsevier
Uveal melanoma (UM) is the most prevalent primary intraocular cancer in adult population.
Primary methods for treatment of UM involves surgery Proton Beam Therapy (PBT), Plaque …

A one-armed phase I dose escalation trial design: personalized vaccination with IKKβ-matured, RNA-loaded dendritic cells for metastatic uveal melanoma

EAT Koch, N Schaft, M Kummer, C Berking… - Frontiers in …, 2022 - frontiersin.org
Uveal melanoma (UM) is an orphan disease with a mortality of 80% within one year upon
the development of metastatic disease. UM does hardly respond to chemotherapy and …

New perspectives for eye-sparing treatment strategies in primary uveal melanoma

K Bilmin, KJ Synoradzki, AM Czarnecka, MJ Spałek… - Cancers, 2021 - mdpi.com
Simple Summary Uveal melanoma is the most common intraocular cancer. The current eye-
sparing treatment options include mostly plaque brachytherapy. However, the effectiveness …

Trends in uveal melanoma presentation and survival during five decades: a nationwide survey of 3898 Swedish patients

V Gill, C Herrspiegel, S Sabazade, M Fili… - Frontiers in …, 2022 - frontiersin.org
Background In contrast to most other cancers, uveal melanoma (UM) is characterized by an
absence of major improvements in patient survival during the last several decades. In this …

Clinical determinants of long-term survival in metastatic uveal melanoma

EAT Koch, A Petzold, A Wessely, E Dippel… - Cancer Immunology …, 2022 - Springer
This study aimed to identify prognostic factors in patients with metastatic uveal melanoma
(UM) that were associated with long-term survival in a real-world setting. A total of 94 …